1527467-07-7
Chemical Structure
27-Alkyne cholesterol
- CAS No.: 1527467-07-7
- Formula:C28H44O
- Molecular Weight:396.65
IUPAC Name: (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((2R,6R)-6-methyloct-7-yn-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey: HOUZLWCQDNDNNE-ZRUUVFCLSA-N
SMILES: C[C@]1(CC2)[C@](CC[C@]1([H])[C@H](C)CCC[C@@H](C)C#C)([H])[C@@](CC=C3C[C@H]4O)([H])[C@@]2([H])[C@]3(CC4)C
Biological Activity: 27-Alkyne cholesterol is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as click chemistry, in the presence of a copper-containing catalyst. Alkyne cholesterol represents a versatile, sensitive, and easy-to-use tool for tracking cellular cholesterol metabolism and localization as it allows for manifold detection methods including mass spectrometry, and fluorescence microscopy.
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27-Alkyne cholesterol | 27-Alkyne cholesterol is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as click chemistry, in the presence of a copper-containing catalyst. Alkyne cholesterol represents a versatile, sensitive, and easy-to-use tool for tracking cellular cholesterol metabolism and localization as it allows for manifold detection methods including mass spectrometry, and fluorescence microscopy. | |||||||||||||||||||||
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Keywords
