55297-87-5
Chemical Structure
Falcarindiol
- CAS No.: 55297-87-5
- Formula:C17H24O2
- Molecular Weight:260.37
IUPAC Name: (3S,8S,Z)-heptadeca-1,9-dien-4,6-diyne-3,8-diol
InChIKey: QWCNQXNAFCBLLV-RCQSYPNMSA-N
SMILES: C=C[C@H](O)C#CC#C[C@@H](O)/C=C\CCCCCCC
Biological Activity: Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol induces apoptosis and autophagy. Falcarindiol has anti-inflammatory, antifungal, anticancer and antidiabetic properties[1][2]. Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Falcarindiol | 97.62% | Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol induces apoptosis and autophagy. Falcarindiol has anti-inflammatory, antifungal, anticancer and antidiabetic properties. Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Similarity Score 1.00
HY-N1976(+)-(3R,8S)-Falcarindiol -
Similarity Score 0.94
HY-N2887Araliadiol -
Similarity Score 0.87
HY-N2789(9Z)-9,17-Octadecadiene-12,14-diyne-1,11,16-triol -
Similarity Score 0.85
HY-N12952Falcarinolone -
Similarity Score 0.84
HY-N1455Falcarinol -
Similarity Score 0.83
HY-N3114Panaxydiol -
Similarity Score 0.83
HY-N15357Falcarindiol 3-acetate -
Similarity Score 0.82
HY-N866411(S),16(R)-Dihydroxyoctadeca-9Z,17-diene12,14-diyn-1-yl acetate -
Similarity Score 0.81
HY-N17382Crithmumdiol -
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References
- [1]. Tingting Lu, et al. Autophagy contributes to falcarindiol-induced cell death in breast cancer cells with enhanced endoplasmic reticulum stress. PLoS One. 2017 Apr 25;12(4):e0176348. [Content Brief]
- [2]. Camilla Bertel Andersen, et al. Falcarindiol Purified From Carrots Leads to Elevated Levels of Lipid Droplets and Upregulation of Peroxisome Proliferator-Activated Receptor-γ Gene Expression in Cellular Models. Front Pharmacol. 2020 Aug 28;11:565524. [Content Brief]
