21 Results for "

Alloxan

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "Alloxan" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W017227
CAS No.: 2244-11-3
Target:  

Proteasome

Research Areas:  

Metabolic Disease Cancer

Alloxan hydrate is a diabetogenic agent to induce diabetes. Alloxan hydrate is a proteasome inhibitor. Alloxan causes diabetes in experimental animals through its ability to destroy the insulin-secreting B-cells of the pancreas .
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1
1 Cited Publications
Cat. No.: HY-W017370
CAS No.: 99-48-9
Carveol is an orally active monoterpenoid alcohol with neuroprotective, antioxidant, anti-inflammatory, anticonvulsant, antidiabetic, hypolipidemic and hepatoprotective activities. Carveol upregulates the expression of Bcl2, downregulates the expression of caspase-3, TNF-α, IL1β and IL6, activates the Nrf2/HO-1 antioxidant signaling pathway, inhibits the RAGE/NF-κB signaling pathway, and suppresses neuroinflammation and neuronal apoptosis. Carveol inhibits α-synuclein aggregation, improves cognitive ability, and inhibits α-amylase activity. Carveol exerts neuroprotective effects in a rat model of Parkinson's disease. Carveol exhibits antidiabetic effects in alloxan-induced diabetic rats. Carveol alleviates PTZ-induced seizures in rats. Carveol can be used in research related to Parkinson's disease, epilepsy, diabetes and ischemic stroke .
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Cat. No.: HY-107754
CAS No.: 7647-17-8
Purity:  99.93%
Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na + transport produced by Alloxan . Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models .
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Cat. No.: HY-W145482
CAS No.: 13224-94-7
3-O-Methyl-D-glucopyranose is a non-metabolizable glucose analog. 3-O-Methyl-D-glucopyranose exerts a protective effect against alloxan-induced damage to rat pancreatic islet β cells. 3-O-Methyl-D-glucopyranose can be used in diabetes research .
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Cat. No.: HY-107482
CAS No.: 34562-97-5
Purity:  98.25%
Synonyms: Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats .
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Cat. No.: HY-W011240
CAS No.: 135-09-1
Synonyms: Methforylthiazidine; Rontyl
Hydroflumethiazide (Methforylthiazidine) is an orally active and potent thiazide diuretic. Hydroflumethiazide possesses the ability to directly stimulate A cell secretion in the normal and alloxan diabetic pancreas .
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Cat. No.: HY-W540188A
Synonyms: Ketomalonic acid calcium trihydrate; Mesoxalic acid calcium trihydrate; Oxomalonic acid calcium trihydrate
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Calcium mesoxalate trihydrate (Ketomalonic acid calcium trihydrate) is an orally active antidiabetic agent. Calcium mesoxalate trihydrate increases pancreatic insulin content. Calcium mesoxalate trihydrate reduces dietary hyperglycemia. Calcium mesoxalate trihydrate inhibits Epinephrine-induced hyperglycemia in rabbits and exacerbates Alloxan (HY-116823)-induced hypoglycemic convulsions. Calcium mesoxalate trihydrate exerts no antidiabetic effect in pancreatectomized dogs and fails to reduce the susceptibility of rabbits to Alloxan-induced diabetes. Calcium mesoxalate trihydrate can be used in diabetes-related research .
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Cat. No.: HY-W101299
CAS No.: 54831-20-8
Research Areas:  

Metabolic Disease

N-Acetyl-D-allo-isoleucine is an amino acid derivative. N-Acetyl-D-allo-isoleucine is promising for research of amino acid metabolism, such as abnormal isoleucine metabolism .
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Cat. No.: HY-128740
CAS No.: 31635-99-1
Mesoxalate sodium monohydrate is an orally active antidiabetic agent. Mesoxalate sodium monohydrate increases pancreatic insulin content. Mesoxalate sodium monohydrate reduces dietary hyperglycemia. Mesoxalate sodium monohydrate inhibits Epinephrine-induced hyperglycemia in rabbits and exacerbates Alloxan (HY-116823)-induced hypoglycemic convulsions. Mesoxalate sodium monohydrate exerts no antidiabetic effect in pancreatectomized dogs and fails to reduce the susceptibility of rabbits to Alloxan-induced diabetes. Mesoxalate sodium monohydrate can be used in diabetes-related research .
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Cat. No.: HY-114634
CAS No.: 473-90-5
Synonyms: Ketomalonic acid; Mesoxalic acid; Oxomalonic acid
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Mesoxalate (Ketomalonic acid) is an orally active antidiabetic agent. Mesoxalate increases pancreatic insulin content. Mesoxalate reduces dietary hyperglycemia. Mesoxalate inhibits Epinephrine-induced hyperglycemia in rabbits and exacerbates Alloxan (HY-116823)-induced hypoglycemic convulsions. Mesoxalate exerts no antidiabetic effect in pancreatectomized dogs and fails to reduce the susceptibility of rabbits to Alloxan-induced diabetes. Mesoxalate can be used in diabetes-related research .
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Cat. No.: HY-107482A
CAS No.: 62936-56-5
Synonyms: Nicotinoyl-GABA sodium; Nicotinoyl-γ-aminobutyric acid sodium; Sodium 4-(nicotinamido)butanoate
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Picamilon sodium is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon sodium improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats .
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Cat. No.: HY-W540188
CAS No.: 21085-60-9
Synonyms: Ketomalonic acid calcium; Mesoxalic acid calcium; Oxomalonic acid calcium
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Calcium mesoxalate (Ketomalonic acid calcium) is an orally active antidiabetic agent. Calcium mesoxalate increases pancreatic insulin content. Calcium mesoxalate reduces dietary hyperglycemia. Calcium mesoxalate inhibits Epinephrine-induced hyperglycemia in rabbits and exacerbates Alloxan (HY-116823)-induced hypoglycemic convulsions. Calcium mesoxalate exerts no antidiabetic effect in pancreatectomized dogs and fails to reduce the susceptibility of rabbits to Alloxan-induced diabetes. Calcium mesoxalate can be used in diabetes-related research .
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Cat. No.: HY-P4910
CAS No.: 1622872-91-6
Target:  

Proteasome Apoptosis

Research Areas:  

Cancer

Baceridin is a proteasome inhibitor and a cyclic hexapeptide. Baceridin can be isolated from the culture medium of Epiphytic Bacillus. Baceridin can inhibit cell cycle progression and induce tumor cell apoptosis through a p53-independent pathway. Baceridin can be used in cancer research .
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Cat. No.: HY-P2120
CAS No.: 79438-64-5
Target:  

Bacterial

Research Areas:  

Others

Pseudobactin A is a non-fluorescent extracellular iron carrier produced by the plant growth-promoting bacterium Pseudomonas B10 .
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Cat. No.: HY-W011240R
CAS No.: 135-09-1
Synonyms: Methforylthiazidine (Standard); Rontyl (Standard)
Hydroflumethiazide (Standard) is the analytical standard of Hydroflumethiazide. This product is intended for research and analytical applications. Hydroflumethiazide (Methforylthiazidine) is an orally active and potent thiazide diuretic. Hydroflumethiazide possesses the ability to directly stimulate A cell secretion in the normal and alloxan diabetic pancreas .
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Cat. No.: HY-116823
CAS No.: 50-71-5
Alloxan is a natural product .
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Cat. No.: HY-W145482S1
3-O-Methyl-D-glucopyranose- 13C6 is 13C-labeled 3-O-Methyl-D-glucopyranose (HY-W145482). 3-O-Methyl-D-glucopyranose is a non-metabolizable glucose analog. 3-O-Methyl-D-glucopyranose exerts a protective effect against alloxan-induced damage to rat pancreatic islet β cells. 3-O-Methyl-D-glucopyranose can be used in diabetes research .
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Cat. No.: HY-W017370R
CAS No.: 99-48-9
Carveol (Standard) is the analytical standard of Carveol. This product is intended for research and analytical applications. Carveol is an orally active monoterpenoid alcohol with neuroprotective, antioxidant, anti-inflammatory, anticonvulsant, antidiabetic, hypolipidemic and hepatoprotective activities. Carveol upregulates the expression of Bcl2, downregulates the expression of caspase-3, TNF-α, IL1β and IL6, activates the Nrf2/HO-1 antioxidant signaling pathway, inhibits the RAGE/NF-κB signaling pathway, and suppresses neuroinflammation and neuronal apoptosis. Carveol inhibits α-synuclein aggregation, improves cognitive ability, and inhibits α-amylase activity. Carveol exerts neuroprotective effects in a rat model of Parkinson's disease. Carveol exhibits antidiabetic effects in alloxan-induced diabetic rats. Carveol alleviates PTZ-induced seizures in rats. Carveol can be used in research related to Parkinson's disease, epilepsy, diabetes and ischemic stroke .
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Cat. No.: HY-P4613
CAS No.: 130674-54-3
Research Areas:  

Others

Fmoc-D-allo-Thr-OH is a derivative of D-allothreonine (HY-W001959), which is commonly used as a building block in solid-phase peptide synthesis (SPPS) .
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Cat. No.: HY-107482R
CAS No.: 34562-97-5
Synonyms: Nicotinoyl-GABA (Standard); Nicotinoyl-γ-aminobutyric acid (Standard)
Research Areas:  

Neurological Disease

Picamilon (Standard) is the analytical standard of Picamilon (HY-107482). This product is intended for research and analytical applications. Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats .
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