34562-97-5
34562-97-5
Chemical Structure
Picamilon
Synonym(s): Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid
- CAS No.: 34562-97-5
- Formula:C10H12N2O3
- Molecular Weight:208.21
IUPAC Name: 4-(nicotinamido)butanoic acid
InChIKey: NAJVRARAUNYNDX-UHFFFAOYSA-N
SMILES: OC(CCCNC(C1=CN=CC=C1)=O)=O
Biological Activity: Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Picamilon | 98.25% | Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats. | ||||||||||||||||||||
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Picamilon (Standard) | ≥98% | Picamilon (Standard) is the analytical standard of Picamilon (HY-107482). This product is intended for research and analytical applications. Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-113353Nicotinuric acid -
Similarity Score 0.84
HY-B1127RBetamipron (Standard) -
Similarity Score 0.84
HY-129445SG-209 -
Similarity Score 0.81
HY-W014505N-(4-Aminobenzoyl)-beta-alanine -
Similarity Score 0.79
HY-116993N-(Hydroxymethyl)nicotinamide -
Similarity Score 0.79
HY-B0341Nicorandil -
Similarity Score 0.79
HY-W016562Hippuric acid -
Similarity Score 0.79
HY-W016562S3Hippuric acid-15N -
Similarity Score 0.79
HY-W747703Hippuric acid-13C6 -
Explore the MedChemAI to find more analogs
References
- [1]. Mirzoian RS, et al. Vliianie pikamilona na krovosnabzhenie kory i mikrotsirkuliatsiiu v sisteme pial'nykh arteriol [Effect of pikamilon on the cortical blood supply and microcirculation in the pial arteriole system]. Biull Eksp Biol Med. 1989 May;107(5):581-2. Russian. [Content Brief]
- [2]. Denisenko, et al. Effects of Picamilon and Isopicamilon on the Formation of Picrotoxin-Induced Convulsive Activity in Rats. Neurophysiology 46, 284–287 (2014).
