Cesium chloride

Cat. No.: HY-107754 Assay: 99.93%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na⁺ transport produced by Alloxan. Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models.

For research use only. We do not sell to patients.

Cesium chloride Chemical Structure

CAS No. : 7647-17-8

Size	Price	Stock	Quantity
5 g	USD 25	In-stock	Estimated Time of Arrival: December 31
10 g	USD 35	In-stock	Estimated Time of Arrival: December 31
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Purity & Documentation
References
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Description

Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na⁺ transport produced by Alloxan^[1]^[2]. Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models^[3].

In Vitro

Cesium chloride (CsCl) decreases the increment of membrane potential, the elevation of intracellular calcium and the upregulation of NOS, ET-1 and VEGF expressions, which are induced by Acrolein^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Cesium Chloride (12 mg/100 g body weight, daily for 30 days; i.p.; male Wistar rats- BOO model) could significantly weaken the effect of XJT (traditional Chinese medicine) on not only the expression of these potassium channels but also the bladder weight, urodynamics, and oxidative stress^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

168.36

Formula

ClCs

CAS No.

7647-17-8

Appearance

Solid

Color

White to off-white

SMILES

[Cs]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (593.97 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.9397 mL	29.6983 mL	59.3965 mL
5 mM	1.1879 mL	5.9397 mL	11.8793 mL
10 mM	0.5940 mL	2.9698 mL	5.9397 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.93%

Select Batch:

Data Sheet (280 KB) SDS (418 KB)

COA (255 KB)

Handling Instructions (2659 KB)

References

[1]. Sun J, Shen W, et al. A Chinese Medicine Formula "Xian-Jia-Tang" for Treating Bladder Outlet Obstruction by Improving Urodynamics and Inhibiting Oxidative Stress through Potassium Channels. Evid Based Complement Alternat Med. 2017;2017:8147258. [Content Brief]

[2]. Soto C, et al. Alloxan decreases intracellular potassium content of the isolated frog skin epithelium. Comp Biochem Physiol C Toxicol Pharmacol. 2001;130(1):19-27. [Content Brief]

[3]. Ouyang JS, Li YP, Li CY, et al. Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells. Free Radic Res. 2012;46(12):1437-1445. [Content Brief]

[4]. O'Brien CE, et al. Cesium-induced QT-interval prolongation in an adolescent. Pharmacotherapy. 2008;28(8):1059-1065. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.9397 mL	29.6983 mL	59.3965 mL	148.4913 mL
	5 mM	1.1879 mL	5.9397 mL	11.8793 mL	29.6983 mL
	10 mM	0.5940 mL	2.9698 mL	5.9397 mL	14.8491 mL
	15 mM	0.3960 mL	1.9799 mL	3.9598 mL	9.8994 mL
	20 mM	0.2970 mL	1.4849 mL	2.9698 mL	7.4246 mL
	25 mM	0.2376 mL	1.1879 mL	2.3759 mL	5.9397 mL
	30 mM	0.1980 mL	0.9899 mL	1.9799 mL	4.9497 mL
	40 mM	0.1485 mL	0.7425 mL	1.4849 mL	3.7123 mL
	50 mM	0.1188 mL	0.5940 mL	1.1879 mL	2.9698 mL
	60 mM	0.0990 mL	0.4950 mL	0.9899 mL	2.4749 mL
	80 mM	0.0742 mL	0.3712 mL	0.7425 mL	1.8561 mL
	100 mM	0.0594 mL	0.2970 mL	0.5940 mL	1.4849 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Cesium chloride Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cesium7647-17-8Potassium ChannelKcsAcardiacarrhythmiasbladderweighturodynamicsoxidativestressInhibitorinhibitorinhibit

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