Calcium mesoxalate trihydrate
Based on 1 Customer Validation
Calcium mesoxalate trihydrate (Ketomalonic acid calcium trihydrate) is an orally active antidiabetic agent. Calcium mesoxalate trihydrate increases pancreatic insulin content. Calcium mesoxalate trihydrate reduces dietary hyperglycemia. Calcium mesoxalate trihydrate inhibits Epinephrine-induced hyperglycemia in rabbits and exacerbates Alloxan (HY-116823)-induced hypoglycemic convulsions. Calcium mesoxalate trihydrate exerts no antidiabetic effect in pancreatectomized dogs and fails to reduce the susceptibility of rabbits to Alloxan-induced diabetes. Calcium mesoxalate trihydrate can be used in diabetes-related research.
For research use only. We do not sell to patients.
- Purity: 98.5%
- Formula: C3H6CaO8
- Molecular Weight:210.15
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 210.15
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Formula C3H6CaO8
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Color White to off-white
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SMILES
O=C(C([O-])=O)C([O-])=O.O.O.O.[Ca+2]
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Synonyms
Ketomalonic acid calcium trihydrate; Mesoxalic acid calcium trihydrate; Oxomalonic acid calcium trihydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
1 M HCl : 33.33 mg/mL (158.60 mM; ultrasonic and warming and heat to 60°C)
Ethanol : < 1 mg/mL (insoluble)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Bernatchez JA, et al. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. The Journal of biological chemistry. 2015 Jan 16;290(3):1474-84. [Content Brief]
[2]. Davis WR, et al. Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. Biochemistry. 2000 Nov 21;39(46):14279-91. [Content Brief]
[3]. TAKEUCHI S. Effect of mesoxalate on insulin content of pancreas. Endocrinol Jpn. 1958 Sep;5(3):177-84. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| 1 M HCl | 1 mM | 4.7585 mL | 23.7925 mL | 47.5851 mL | 118.9626 mL |
| 5 mM | 0.9517 mL | 4.7585 mL | 9.5170 mL | 23.7925 mL | |
| 10 mM | 0.4759 mL | 2.3793 mL | 4.7585 mL | 11.8963 mL | |
| 15 mM | 0.3172 mL | 1.5862 mL | 3.1723 mL | 7.9308 mL | |
| 20 mM | 0.2379 mL | 1.1896 mL | 2.3793 mL | 5.9481 mL | |
| 25 mM | 0.1903 mL | 0.9517 mL | 1.9034 mL | 4.7585 mL | |
| 30 mM | 0.1586 mL | 0.7931 mL | 1.5862 mL | 3.9654 mL | |
| 40 mM | 0.1190 mL | 0.5948 mL | 1.1896 mL | 2.9741 mL | |
| 50 mM | 0.0952 mL | 0.4759 mL | 0.9517 mL | 2.3793 mL | |
| 60 mM | 0.0793 mL | 0.3965 mL | 0.7931 mL | 1.9827 mL | |
| 80 mM | 0.0595 mL | 0.2974 mL | 0.5948 mL | 1.4870 mL | |
| 100 mM | 0.0476 mL | 0.2379 mL | 0.4759 mL | 1.1896 mL |
Calcium mesoxalate trihydrate Related Classifications
HY-W540188A Related Classifications
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