Mesoxalate
Based on 1 publication(s) in Google Scholar
Mesoxalate (Ketomalonic acid) is an orally active antidiabetic agent. Mesoxalate increases pancreatic insulin content. Mesoxalate reduces dietary hyperglycemia. Mesoxalate inhibits Epinephrine-induced hyperglycemia in rabbits and exacerbates Alloxan (HY-116823)-induced hypoglycemic convulsions. Mesoxalate exerts no antidiabetic effect in pancreatectomized dogs and fails to reduce the susceptibility of rabbits to Alloxan-induced diabetes. Mesoxalate can be used in diabetes-related research.
For research use only. We do not sell to patients.
- CAS No.: 473-90-5
- Formula: C3H2O5
- Molecular Weight:118.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) Mesoxalate
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Biological Activity
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 473-90-5
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Molecular Weight 118.04
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Formula C3H2O5
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SMILES
O=C(C(C(O)=O)=O)O
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Synonyms
Ketomalonic acid; Mesoxalic acid; Oxomalonic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Purity & Documentation
References
[1]. Bernatchez JA, et al. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. The Journal of biological chemistry. 2015 Jan 16;290(3):1474-84. [Content Brief]
[2]. Davis WR, et al. Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. Biochemistry. 2000 Nov 21;39(46):14279-91. [Content Brief]
[3]. TAKEUCHI S. Effect of mesoxalate on insulin content of pancreas. Endocrinol Jpn. 1958 Sep;5(3):177-84. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mesoxalate Related Classifications
HY-114634 Related Classifications
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