Mesoxalate
Mesoxalate (Ketomalonic acid) a dicarboxylic acid and a ketonic acid which blocks HIV-1 reverse transcriptase (RT), with the IC50 of 2.2 μM.
For research use only. We do not sell to patients.
- CAS No.: 473-90-5
- Formula: C3H2O5
- Molecular Weight:118.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 473-90-5
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Molecular Weight 118.04
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Formula C3H2O5
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SMILES
O=C(C(C(O)=O)=O)O
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Synonyms
Ketomalonic acid; Mesoxalic acid; Oxomalonic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Jean A Bernatchez, et al. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. J Biol Chem. 2015 Jan 16;290(3):1474-84. [Content Brief]
[2]. W R Davis, et al. Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. Biochemistry. 2000 Nov 21;39(46):14279-91. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)