Mesoxalate sodium monohydrate
Based on 1 Customer Validation
Mesoxalate sodium monohydrate is an orally active antidiabetic agent. Mesoxalate sodium monohydrate increases pancreatic insulin content. Mesoxalate sodium monohydrate reduces dietary hyperglycemia. Mesoxalate sodium monohydrate inhibits Epinephrine-induced hyperglycemia in rabbits and exacerbates Alloxan (HY-116823)-induced hypoglycemic convulsions. Mesoxalate sodium monohydrate exerts no antidiabetic effect in pancreatectomized dogs and fails to reduce the susceptibility of rabbits to Alloxan-induced diabetes. Mesoxalate sodium monohydrate can be used in diabetes-related research.
For research use only. We do not sell to patients.
- CAS No.: 31635-99-1
- Formula: C3H2Na2O6
- Molecular Weight:180.02
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 31635-99-1
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Appearance Solid
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Molecular Weight 180.02
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Formula C3H2Na2O6
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Color White to off-white
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SMILES
O=C([O-])C(O)(O)C([O-])=O.[Na+].[Na+]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 30 mg/mL (166.65 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 6.67 mg/mL (37.05 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Bernatchez JA, et al. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. The Journal of biological chemistry. 2015 Jan 16;290(3):1474-84. [Content Brief]
[2]. Davis WR, et al. Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. Biochemistry. 2000 Nov 21;39(46):14279-91. [Content Brief]
[3]. TAKEUCHI S. Effect of mesoxalate on insulin content of pancreas. Endocrinol Jpn. 1958 Sep;5(3):177-84. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.5549 mL | 27.7747 mL | 55.5494 mL | 138.8735 mL |
| 5 mM | 1.1110 mL | 5.5549 mL | 11.1099 mL | 27.7747 mL | |
| 10 mM | 0.5555 mL | 2.7775 mL | 5.5549 mL | 13.8873 mL | |
| 15 mM | 0.3703 mL | 1.8516 mL | 3.7033 mL | 9.2582 mL | |
| 20 mM | 0.2777 mL | 1.3887 mL | 2.7775 mL | 6.9437 mL | |
| 25 mM | 0.2222 mL | 1.1110 mL | 2.2220 mL | 5.5549 mL | |
| 30 mM | 0.1852 mL | 0.9258 mL | 1.8516 mL | 4.6291 mL | |
| 40 mM | 0.1389 mL | 0.6944 mL | 1.3887 mL | 3.4718 mL | |
| 50 mM | 0.1111 mL | 0.5555 mL | 1.1110 mL | 2.7775 mL | |
| 60 mM | 0.0926 mL | 0.4629 mL | 0.9258 mL | 2.3146 mL | |
| 80 mM | 0.0694 mL | 0.3472 mL | 0.6944 mL | 1.7359 mL | |
| 100 mM | 0.0555 mL | 0.2777 mL | 0.5555 mL | 1.3887 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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