Mesoxalate sodium monohydrate
Based on 1 Customer Validation
Mesoxalate sodium monohydrate is an orally active antidiabetic agent. Mesoxalate sodium monohydrate increases pancreatic insulin content. Mesoxalate sodium monohydrate reduces dietary hyperglycemia. Mesoxalate sodium monohydrate inhibits Epinephrine-induced hyperglycemia in rabbits and exacerbates Alloxan (HY-116823)-induced hypoglycemic convulsions. Mesoxalate sodium monohydrate exerts no antidiabetic effect in pancreatectomized dogs and fails to reduce the susceptibility of rabbits to Alloxan-induced diabetes. Mesoxalate sodium monohydrate can be used in diabetes-related research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 31635-99-1
- 分子式: C3H2Na2O6
- 分子量:180.02
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 31635-99-1
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性状 Solid
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分子量 180.02
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分子式 C3H2Na2O6
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Color White to off-white
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SMILES
O=C([O-])C(O)(O)C([O-])=O.[Na+].[Na+]
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別名
メソシュウ酸ナトリウム 一水和物
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
H2O : 30 mg/mL (166.65 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 6.67 mg/mL (37.05 mM); Clear solution; Need ultrasonic
純度とドキュメンテーション
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データシート (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Bernatchez JA, et al. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. The Journal of biological chemistry. 2015 Jan 16;290(3):1474-84. [Content Brief]
[2]. Davis WR, et al. Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. Biochemistry. 2000 Nov 21;39(46):14279-91. [Content Brief]
[3]. TAKEUCHI S. Effect of mesoxalate on insulin content of pancreas. Endocrinol Jpn. 1958 Sep;5(3):177-84. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.5549 mL | 27.7747 mL | 55.5494 mL | 138.8735 mL |
| 5 mM | 1.1110 mL | 5.5549 mL | 11.1099 mL | 27.7747 mL | |
| 10 mM | 0.5555 mL | 2.7775 mL | 5.5549 mL | 13.8873 mL | |
| 15 mM | 0.3703 mL | 1.8516 mL | 3.7033 mL | 9.2582 mL | |
| 20 mM | 0.2777 mL | 1.3887 mL | 2.7775 mL | 6.9437 mL | |
| 25 mM | 0.2222 mL | 1.1110 mL | 2.2220 mL | 5.5549 mL | |
| 30 mM | 0.1852 mL | 0.9258 mL | 1.8516 mL | 4.6291 mL | |
| 40 mM | 0.1389 mL | 0.6944 mL | 1.3887 mL | 3.4718 mL | |
| 50 mM | 0.1111 mL | 0.5555 mL | 1.1110 mL | 2.7775 mL | |
| 60 mM | 0.0926 mL | 0.4629 mL | 0.9258 mL | 2.3146 mL | |
| 80 mM | 0.0694 mL | 0.3472 mL | 0.6944 mL | 1.7359 mL | |
| 100 mM | 0.0555 mL | 0.2777 mL | 0.5555 mL | 1.3887 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mesoxalate sodium monohydrate 関連分類
HY-128740 関連分類
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