2244-11-3
2244-11-3
Chemical Structure
Alloxan hydrate
- CAS No.: 2244-11-3
- Formula:C4H4N2O5
- Molecular Weight:160.08
IUPAC Name: 4,6-dihydroxypyrimidine-2,5-dione hydrate
InChIKey: DSXMTJRUNLATRP-UHFFFAOYSA-N
SMILES: O=C(C(O)=N1)C(O)=NC1=O.O
Biological Activity: Alloxan hydrate is a diabetogenic agent to induce diabetes. Alloxan hydrate is a proteasome inhibitor. Alloxan causes diabetes in experimental animals through its ability to destroy the insulin-secreting B-cells of the pancreas[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Alloxan hydrate | 99.99% | Alloxan hydrate is a diabetogenic agent to induce diabetes. Alloxan hydrate is a proteasome inhibitor. Alloxan causes diabetes in experimental animals through its ability to destroy the insulin-secreting B-cells of the pancreas. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.59
HY-W0105541,4-Cyclohexanedione -
Similarity Score 0.59
HY-W007466Cyclohexane-1,3-dione -
Similarity Score 0.59
HY-W777266Cyclohexane-1,3-dione-13C3 -
Similarity Score 0.59
HY-W777928Cyclohexane-1,3-dione-13C6 -
Similarity Score 0.56
HY-Y0262AOxalic acid diammonium monohydrate -
Similarity Score 0.56
HY-W094712Potassium oxalate monohydrate -
Similarity Score 0.56
HY-Y0262DOxalic acid calcium monohydrate,99% -
Similarity Score 0.56
HY-753551,3-Cyclopentanedione -
Similarity Score 0.55
HY-W002860Cycloheptane-1,3-dione -
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References
- [1]. Zhou W, et al. Diabetogenic agent alloxan is a proteasome inhibitor. Biochem Biophys Res Commun. 2017;488(2):400-406. [Content Brief]
- [2]. Munday R, et al. The relationship between the physicochemical properties and the biological effects of alloxan and several N-alkyl substituted alloxan derivatives. J Endocrinol. 1993;139(1):153-163. [Content Brief]
