1 Result for "

Antileishmanial agent-19

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Antileishmanial agent-19" in MCE Product Catalog:

Cat. No.: HY-155520
CAS No.: 3049715-81-0
Target:  

Parasite

Research Areas:  

Infection

Antileishmanial agent-19 (Compound F27) is an antileishmanial agent, with a IC50 of 3.39 μM for L. donovani promastigotes. Antileishmanial agent-19 inhibits Leishmania prolyl-tRNA synthetase. Antileishmanial agent-19 inhibits host PI3K/Akt/CREB axis-mediated IL-10 secretion. Antileishmanial agent-19 induces autophagy-mediated apoptosis in L. donovani promastigotes. Antileishmanial agent-19 reduces parasite burden in L.d-infected animals .
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