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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
Atorvastatin calcium
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "Atorvastatin calcium" in MCE Product Catalog:
73
73 Cited Publications
Target:
Research Areas:
Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver.
Research Areas:
2-Hydroxy atorvastatin calcium salt is an orally active OATP1B1 substrate and inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (3-hydroxy-3-methylglutaryl-coenzyme A reductase). 2-Hydroxy atorvastatin calcium salt enters cells via OATP1B1-mediated cellular uptake and inhibits de novo hepatic cholesterol synthesis. As an active metabolite of Atorvastatin (HY-B0589), 2-Hydroxy atorvastatin calcium salt contributes to the inhibitory activity against plasma HMG-CoA reductase. 2-Hydroxy atorvastatin calcium salt can be biotransformed into an inactive lactone form, which can be hydrolyzed back to its active acid form chemically or enzymatically. 2-Hydroxy atorvastatin (calcium salt) can be used in the research of hypercholesterolemia .
Cat. No.: HY-144577S
CAS No.: 265989-47-7
Cat. No.: HY-143816S
CAS No.: 265989-45-5
Cat. No.: HY-135375
CAS No.: 887196-29-4
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Research Areas:
O-Methyl Atorvastatin (hemicalcium) is an impurity of Atorvastatin. Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has the ability to effectively decrease blood lipids .
Cat. No.: HY-Z19630
CAS No.: 887196-25-0
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Atorvastatin impurity 7 calcium is an impurity of Atorvastatin calcium.
Cat. No.: HY-Z19634
CAS No.: 1046118-41-5
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Research Areas:
Atorvastatin impurity 6 calcium is an impurity of Atorvastatin calcium.
Cat. No.: HY-Z7628
CAS No.: 433289-83-9
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Atorvastatin impurity 2 calcium is an impurity of Atorvastatin calcium.
Cat. No.: HY-141987S
CAS No.: 777841-55-1
Synonyms: Atorvastatin impurity K-d5
Cat. No.: HY-141987S1
Cat. No.: HY-143840S
CAS No.: 1276537-19-9
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
