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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
BIA 2-005-d3
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "BIA 2-005-d3" in MCE Product Catalog:
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Opicapone (BIA 9-1067) is a potent third-generation catechol-O-methyltransferase (COMT) inhibitor for the research of Parkinson's disease and motor fluctuations. Opicapone decreases the ATP content of the cells with an IC50 of 98 μM .
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2 Cited Publications
Cat. No.: HY-19740
CAS No.: 1233855-46-3
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BIA 10-2474 is an inhibitor of fatty acid amide hydrolase (FAAH) with IC50 values of 50 to 70mg/kg in various rat brain regions.
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BIO-acetoxime (BIA) is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/β. BIO-acetoxime has anticonvulsant and anti-infection activity.
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Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.
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1 Cited Publications
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7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with an IC50 of ~1-3 μM .
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1 Cited Publications
Synonyms: BIA 2-005; GP 47779
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Licarbazepine (BIA 2-005; GP 47779) is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects .
Synonyms: LTI-291; BIA 28-6156
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Pariceract (LTI-291) is an activator of glucocerebrosidase (Gcase), with activation rates of more than 60% (1 μM) and between 10%-20% (0.1 μM). Pariceract can be used for Parkinson's disease and endometriosis research .
Cat. No.: HY-B0703
CAS No.: 236395-14-5
Synonyms: BIA 2-093
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Eslicarbazepine acetate (BIA 2-093), an antiepileptic agent, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.
Synonyms: BIA 5-1058
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Zamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 values of 73.8 μM and 17.0 μM, respectively . Zamicastat reduces high blood pressure .
Synonyms: BIA 3-202
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Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinson's disease .
Synonyms: BIA 5-453 hydrochloride
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Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor with an IC50 value of 107 nM . Etamicastat can be used in the research of cardiovascular diseases .
Cat. No.: HY-114703S1
Synonyms: BIA 2-194-d4
Cat. No.: HY-108506R
CAS No.: 29331-92-8
Synonyms: BIA 2-005 (Standard); GP 47779 (Standard)
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Licarbazepine (Standard) is the analytical standard of Licarbazepine. This product is intended for research and analytical applications. Licarbazepine (BIA 2-005; GP 47779) is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects .
Cat. No.: HY-14838
CAS No.: 760173-05-5
Synonyms: BIA 5-453
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Research Areas:
Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor with an IC50 value of 107 nM . Etamicastat can be used in the research of cardiovascular diseases .
Cat. No.: HY-14896R
CAS No.: 923287-50-7
Synonyms: BIA 9-1067 (Standard)
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Opicapone (Standard) is the analytical standard of Opicapone. This product is intended for research and analytical applications. Opicapone (BIA 9-1067) is a potent third-generation catechol-O-methyltransferase (COMT) inhibitor for the research of Parkinson's disease and motor fluctuations. Opicapone decreases the ATP content of the cells with an IC50 of 98 μM .
Cat. No.: HY-108506S2
CAS No.: 1188265-49-7
Synonyms: BIA 2-005-d4-1; GP 47779-d4-1
Cat. No.: HY-119224
CAS No.: 359783-06-5
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BIA 3-335 is an inhibitor for catechol-O-methyltransferase (COMT), and can be used in research about Parkinson's disease .
Cat. No.: HY-B0703R
CAS No.: 236395-14-5
Synonyms: BIA 2-093 (Standard)
Research Areas:
Eslicarbazepine acetate (Standard) is the analytical standard of Eslicarbazepine acetate. This product is intended for research and analytical applications. Eslicarbazepine acetate (BIA 2-093), an antiepileptic agent, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.
Cat. No.: HY-108506S4
CAS No.: 1261393-17-2
Synonyms: BIA 2-005-d8; GP 47779-d8
Cat. No.: HY-114937
CAS No.: 186694-45-1
Synonyms: BIA 2-059; (R)-Licarbazepine acetate
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(R)-Eslicarbazepine acetate (BIA 2-059) is the R-enantiomer of Eslicarbazepine acetate (HY-B0703). Eslicarbazepine acetate is an antiepileptic agent, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
