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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
156 Results for "
Biological probes
" in MedChemExpress (MCE) Product Catalog:
Products (156)
156 Results for "Biological probes" in MCE Product Catalog:
34
34 Publications Verification
14
Research Areas:
Fluorescein (Uranine) sodium is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) sodium is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes .
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11
11 Cited Publications
Cat. No.: HY-19313
CAS No.: 1793053-37-8
Target:
Research Areas:
LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. LLY-507 potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 <15 nM. LLY-507 serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes .
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7 Cited Publications
7
7 Cited Publications
Cat. No.: HY-W127715
CAS No.: 71206-95-6
1
1 Cited Publications
Cat. No.: HY-D1730
CAS No.: 1374019-99-4
Target:
Research Areas:
AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .
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1
1 Cited Publications
Cat. No.: HY-D1730A
1
1 Cited Publications
Cat. No.: HY-D1601
CAS No.: 98907-26-7
1
1 Cited Publications
Synonyms: Benzo[def]phenanthrene
1
1 Cited Publications
Cat. No.: HY-N2464
CAS No.: 34612-38-9
Synonyms: Amylotetraose; Fujioligo 450; α-1,4-Tetraglucose
1
1 Cited Publications
Target:
Research Areas:
MN551 is a covalent modulator of SOCS2 and CISH, with selectivity for SOCS2 and CISH over SOCS4. MN551 covalently modifies Cys111 in the SH2 domain of SOCS2 and Cys144 in the EF loop of the CISH SH2 domain, while only minimally modifying Cys471 in the BG loop of the SOCS6 SH2 domain. MN551 increases the thermal stability of the recombinant SOCS2-ElonginB-ElonginC complex and competitively blocks the binding of SOCS2 to its substrate; when delivered via the prodrug MN714, it blocks the intracellular recruitment of substrates by SOCS2. MN551 can serve as a chemical probe for investigating the biological functions of SOCS2 and its CRL5 complex, and also act as an E3 ligase-binding module in proteolysis-targeting chimeras (PROTACs) .
Cat. No.: HY-D1378
CAS No.: 959839-06-6
Cat. No.: HY-NP080
Synonyms: SNA
Cat. No.: HY-NP087
Synonyms: LCA
Cat. No.: HY-D2775
CAS No.: 3047612-66-5
Cat. No.: HY-NP0181
Synonyms: MAL II (Biotinylated)
Cat. No.: HY-143678
CAS No.: 2468149-70-2
Target:
Research Areas:
Citrulline-specific probe-biotin is a biotinylated probe for detection of citrulline. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-biotin is a biological probe that can identify diseases showing abnormal increases in PAD activity .
Cat. No.: HY-D2344
CAS No.: 325721-44-6
Synonyms: 3-Benzothiazole-daphnetin
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
