129-00-0
Chemical Structure
Pyrene
Synonym(s): Benzo[def]phenanthrene
- CAS No.: 129-00-0
- Formula:C16H10
- Molecular Weight:202.26
IUPAC Name: pyrene
InChIKey: BBEAQIROQSPTKN-UHFFFAOYSA-N
SMILES: C12=CC=C3C=CC=C4C=CC(C2=C34)=CC=C1
Biological Activity: Pyrene is a polycyclic aromatic hydrocarbon (PAH) composed of four fused benzene rings. It has a distinct aromatic odor, produced by incomplete combustion of organic matter. Pyrene exhibits strong fluorescence, emitting in the blue region of the spectrum, making it useful as a probe for studying molecular interactions in solution and on surfaces. Pyrene is also used as a model compound for the study of PAHs in various environments and biological systems because of its ubiquity in these environments. However, long-term exposure to pyrene has been associated with potential health risks, including carcinogenicity and mutagenicity.
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Pyrene | 99.89% | Pyrene is a polycyclic aromatic hydrocarbon (PAH) composed of four fused benzene rings. It has a distinct aromatic odor, produced by incomplete combustion of organic matter. Pyrene exhibits strong fluorescence, emitting in the blue region of the spectrum, making it useful as a probe for studying molecular interactions in solution and on surfaces. Pyrene is also used as a model compound for the study of PAHs in various environments and biological systems because of its ubiquity in these environments. However, long-term exposure to pyrene has been associated with potential health risks, including carcinogenicity and mutagenicity. | ||||||||||||||||||||
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Pyrene (Standard) | 99.82% | Pyrene (Standard) is the analytical standard of Pyrene. This product is intended for research and analytical applications. Pyrene is a polycyclic aromatic hydrocarbon (PAH) composed of four fused benzene rings. It has a distinct aromatic odor, produced by incomplete combustion of organic matter. Pyrene exhibits strong fluorescence, emitting in the blue region of the spectrum, making it useful as a probe for studying molecular interactions in solution and on surfaces. Pyrene is also used as a model compound for the study of PAHs in various environments and biological systems because of its ubiquity in these environments. However, long-term exposure to pyrene has been associated with potential health risks, including carcinogenicity and mutagenicity. | ||||||||||||||||||||
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Pyrene-d10 | 99.88% | Pyrene-d10 is the deuterium labeled Pyrene. | ||||||||||||||||||||
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Benzo[a]pyrene | 99.98% | Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies. | ||||||||||||||||||||
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Benzo[a]pyrene-d12 | 99.30% | Benzo[a]pyrene-d12 is the deuterium labeled Benzo[a]pyrene. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies. | ||||||||||||||||||||
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Chrysene-d12 | 99.71% | Chrysene-d12 is the deuterium labeled Chrysene. Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties. | ||||||||||||||||||||
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1-Ethynylpyrene | 98.37% | 1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively. 1-Ethynylpyrene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Benzo[e]pyrene-d12 | 98.9% | Benzo[e]pyrene-d12 is the deuterium labeled Benzo[e]pyrene. | ||||||||||||||||||||
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NSC 89275-d12 | NSC 89275-d12 is the deuterium labeled NSC 89275. | |||||||||||||||||||||
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Phenanthrene-d10 | 99.46% | Phenanthrene-d10 is the deuterium labeled Phenanthrene. Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) and has been frequently used as an indicator for monitoring PAH contaminated matrices. Phenanthrene induces oxidative stress and inflammation. | ||||||||||||||||||||
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1-Pyrenemethanol | 98.77% | 1-Pyrenemethanol is an organic compound that can be used to prepare graphene films with excellent thermal conductivity, flexibility and mechanical properties. 1-Pyrenemethanol binds to graphene oxide sheets through hydrogen bonds and π-π interactions to form GO-PyM films, increasing the dispersion and stability of the material. | ||||||||||||||||||||
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Benzo[c]phenanthrene | Benzo[c]phenanthrene has carcinogenic activity. Benzo[c]phenanthrene can be used as a substrate or intermediate. | |||||||||||||||||||||
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Benz[a]anthracene-d12 | 99.74% | Benz[a]anthracene-d12 (Tetraphene-d12) is the deuterated-labeled Benz[a]anthracene (HY-W012278). Benz[a]anthracene (Tetraphene) is a polycyclic aromatic hydrocarbon pollutant and also a ligand of aryl hydrocarbon receptor 2 (AHR2), with a pIC50 of 7.319. Benz[a]anthracene can be detected in spruce needles near aluminum smelters. Exposure to Benz[a]anthracene during zebrafish embryonic stage activates the AHR-CYP1A signaling pathway and induces AHR2 expression, leading to social behavioral deficits that persist into adulthood, accompanied by impaired neuro-immune interaction, while anxiety levels remain unaffected. Benz[a]anthracene can be used in studies related to PAH environmental toxicology, developmental neurotoxicity and biodegradation. | ||||||||||||||||||||
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1-Hydroxypyrene | 99.76% | 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for aryl hydrocarbon receptor (AhR) and can lead to renal fibrosis. | ||||||||||||||||||||
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1-Hydroxypyrene-d9 | 99.64% | 1-Hydroxypyrene-d9 is the deuterium labeled 1-Hydroxypyrene (HY-W014075). 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for aryl hydrocarbon receptor (AhR) and can lead to renal fibrosis. | ||||||||||||||||||||
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Perylene-d12 | 99.71% | Perylene-d12 is the deuterium labeled Perylene. | ||||||||||||||||||||
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1-Pyrenamin | 1-Pyrenamin (1-Pyrenamine purified by sublimation) is utilized to create highly efficient and stable catalyst supports in direct methanol fuel cells through noncovalent functionalization of graphite nanosheets. | |||||||||||||||||||||
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1-Pyrenamin-d9 | 1-Pyrenamin-d9 is the deuterium labeled 1-Pyrenamin. | |||||||||||||||||||||
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1-Chloromethylpyrene | 98.0% | 1-Chloromethylpyrene is an alkylating agent that enters the DNA double helix structure through intercalation, forms covalent bonds with electrophilic groups, resulting in DNA cross-linking, thereby inhibiting the proliferation of tumor cells. | ||||||||||||||||||||
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1-(Bromomethyl)pyrene | 1-(Bromomethyl)pyrene is a Br compound with antitumor activity. 1-(Bromomethyl)pyrene is widely used in the synthesis of fluorophores for the fluorescent sensing of variety of analytes. 1-(Bromomethyl)pyrene can be also used in the synthesis of photoinitiators (PIs). | |||||||||||||||||||||
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1-Methylpyrene | 99.51% | 1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba | ||||||||||||||||||||
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1-Ethenylpyrene | 99.62% | 1-Ethenylpyrene (1-Vinylpyrene) is an anti-chemical carcinogen that inhibits the formation of skin tumors initiated by either DMBA (HY-W011845) or Benzo[a]pyrene (HY-107377). | ||||||||||||||||||||
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