Benzo[a]pyrene-d12
Based on 1 Customer Validation
Benzo[a]pyrene-d12 is the deuterium labeled Benzo[a]pyrene. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies.
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- Pureté: 99.30%
- CAS No.: 63466-71-7
- Formule: C20D12
- Masse moléculaire:264.38
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Stockage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
![Benzo[a]pyrene-d12 Chemical Structure](https://file.medchemexpress.com/product_pic/hy-107377s.gif "Click to View Benzo[a]pyrene-d12 Chemical Structure")
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 63466-71-7
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Unlabeled Cas 50-32-8
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Appearance Solid
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Masse moléculaire 264.38
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Formule C20D12
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Color Light yellow to yellow
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SMILES
[2H]C1=C2C([2H])=C([2H])C([2H])=C3C([2H])=C([2H])C4=C([2H])C5=C([2H])C([2H])=C([2H])C([2H])=C5C(C4=C32)=C1[2H]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Pureté et documentation
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Fiche technique (273 KB)
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SDS (701 KB)
- English - EN (701 KB)
- Français - FR (701 KB)
- Deutsch - DE (701 KB)
- Norwegian - NO (701 KB)
- Español - ES (701 KB)
- Swedish - SV (701 KB)
- Italian - IT (701 KB)
- Korean - KR (701 KB)
- Portuguese - PT (701 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Saeko Onami, et al. Dosimetry for lung tumorigenesis induced by urethane, 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and benzo[a]pyrene (B[a]P) in A/JJmsSlc mice. J Toxicol Pathol. 2017 Jul; 30(3): 209–216. [Content Brief]
[3]. Yeo CD, et al. Roflumilast treatment inhibits lung carcinogenesis in benzo(a)pyrene-induced murine lung cancer model. Eur J Pharmacol. 2017 Oct 5812:189 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Benzo[a]pyrene-d12 Related Classifications
HY-107377S Related Classifications
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