63466-71-7
![Benzo[a]pyrene-d<sub>12</sub> Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-107377s.gif "Benzo[a]pyrene-d<sub>12</sub> Chemical Structure")
63466-71-7
Chemical Structure
Benzo[a]pyrene-d12
- CAS No.: 63466-71-7
- Formula:C20D12
- Molecular Weight:264.38
IUPAC Name: benzo[pqr]tetraphene-d12
InChIKey: FMMWHPNWAFZXNH-AQZSQYOVSA-N
SMILES: [2H]C1=C2C([2H])=C([2H])C([2H])=C3C([2H])=C([2H])C4=C([2H])C5=C([2H])C([2H])=C([2H])C([2H])=C5C(C4=C32)=C1[2H]
Biological Activity: Benzo[a]pyrene-d12 is the deuterium labeled Benzo[a]pyrene[1]. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies[2][3].
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Benzo[a]pyrene-d12 | 99.30% | Benzo[a]pyrene-d12 is the deuterium labeled Benzo[a]pyrene. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies. | ||||||||||||||||||||
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Benzo[a]pyrene (Standard) | 99.76% | Benzo[a]pyrene (Standard) is the analytical standard of Benzo[a]pyrene. This product is intended for research and analytical applications. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies. | ||||||||||||||||||||
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Benzo[a]pyrene | 99.98% | Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Saeko Onami, et al. Dosimetry for lung tumorigenesis induced by urethane, 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and benzo[a]pyrene (B[a]P) in A/JJmsSlc mice. J Toxicol Pathol. 2017 Jul; 30(3): 209–216. [Content Brief]
- [3]. Yeo CD, et al. Roflumilast treatment inhibits lung carcinogenesis in benzo(a)pyrene-induced murine lung cancer model. Eur J Pharmacol. 2017 Oct 5812:189 [Content Brief]
