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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
Biotransformation,
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "Biotransformation," in MCE Product Catalog:
Cat. No.: HY-W015590
CAS No.: 614-75-5
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Monophenols Ketones, Aldehydes, Acids Disease markers Endocrine diseases Phenols Nervous System Disorder Endogenous metabolite
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Cat. No.: HY-P2816
CAS No.: 37278-89-0
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Xylanase is an enzyme targeting 1,4-β-D-xylan that randomly cleaves the β-1,4 backbone of xylan, a complex polysaccharide in plant cell walls. Xylanase finds applications in the food, feed and industrial sectors, including pulp and paper processing, baking, animal feed improvement, and biotransformation of waste .
Cat. No.: HY-173351
CAS No.: 2901806-51-5
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G-6599 is a monovalent molecular glue-like degrader of SMARCA2/SMARCA4. G-6599 covalently binds to a specific cysteine residue of the E3 ligase FBXO22 in a biotransformation-independent manner, promotes the formation of a ternary complex with SMARCA2/A4, and achieves efficient and specific degradation of the two proteins via the ubiquitin-proteasome pathway. G-6599 is applicable to the research of androgen-dependent prostate cancer and mutant non-small cell lung cancer .
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Diaphorase, Recombinant microorganisms can be obtained from anaerobic sludge organisms. Diaphorase catalyzes biotransformation of hexahydro-1,3, 5-trinitro-1,3, 5-triazine (RDX) by denitrification .
Synonyms: BIA 3-202
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Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinson's disease .
Cat. No.: HY-W013058
CAS No.: 84852-53-9
Synonyms: DBDPE; 1,2-Bis(perbromophenyl)ethane
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Decabromodiphenyl ethane (DBDPE) is a brominated flame retardant. Decabromodiphenyl ethane induces ROS-related cytotoxicity and apoptosis in human hepatoma cells, causes hepatocyte damage through oxidative stress, endoplasmic reticulum stress and decreased CYP3A expression, and accumulates and undergoes biotransformation in animal tissues. Decabromodiphenyl ethane can be used to study the environmental toxicology and biological effects of brominated flame retardants .
Cat. No.: HY-N7921
CAS No.: 1006683-97-1
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β-N-Acetylhexosaminidase, Porcine kidney is a glycosidase with transglycosylation activity, used to generate health-beneficial human milk oligosaccharides, and it effectively interacts with low molecular weight sugar alcohols (such as glycerol, erythritol, and xylitol). The enzyme exhibits optimal activity at pH 5 and 40 °C, and shows high thermal stability (up to 55°C) when bound to the cell wall. β-N-Acetylhexosaminidase holds promise for applications in the biotransformation of Chitin (HY-126389) and research in the food health sector .
Cat. No.: HY-W102516
CAS No.: 1162-56-7
Synonyms: Δ6-Progesterone
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Cat. No.: HY-W153159
CAS No.: 13062-76-5
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Cat. No.: HY-N16639
CAS No.: 105330-51-6
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Cat. No.: HY-N11677
CAS No.: 1035154-52-9
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Cat. No.: HY-119963A
CAS No.: 7299-41-4
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trans-β-Terpineol is a cyclic monoterpene alcohol present in Greek propolis and the essential oil of Peganum harmala seeds, with biological activities. trans-β-Terpineol serves as a substrate for biotransformation in tobacco suspension cells, where allylic hydroxylation occurs at specific sites. trans-β-Terpineol can be isolated from the leaves of Euryops arabicus. Terpineol (HY-N7851) exhibits antioxidant and antibacterial activities, and trans-β-terpineol is the bioactive compound responsible for the antibacterial effect in Euryops arabicus .
Cat. No.: HY-154916
CAS No.: 139958-51-3
Synonyms: 13-DMT; 13-O-Demethyl FK 506
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13-O-Desmethyl tacrolimus (13-DMT; 13-O-Demethyl FK 506) is the major metabolite of Tacrolimus (HY-13756) formed via cytochrome P450 3A-mediated biotransformation. The ratio of 13-O-Desmethyl tacrolimus to Tacrolimus serves as a biomarker for myelotoxicity and hepatotoxicity .
Cat. No.: HY-W153897
CAS No.: 370-98-9
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Alkaloids Human Gut Microbiota Metabolites Leguminosae Other Alkaloids Acacia auriculiformis A.Cunn. ex Benth Plants Endogenous metabolite
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Cat. No.: HY-N8911
CAS No.: 121927-96-6
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Cat. No.: HY-123340
CAS No.: 56784-39-5
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Ozolinone is a diuretic metabolite formed by biotransformation of the diuretic elkapin in mammals and exerts a potent diuretic effect in a variety of species .
Cat. No.: HY-139428
CAS No.: 34783-31-8
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Hydroxydehydro Nifedipine Carboxylate is an inactive metabolite formed by the oxidative biotransformation of Nifedipine (HY-B0284) in the human body .
Cat. No.: HY-N13220
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Soybean Extract is a soybean extract, and its components include: Isoflavone. Soybean Extract has an increased content of isoflavone aglycones after biotransformation, which is an estrogen-like bioactive compound with effective type I collagen enhancement. .
Cat. No.: HY-N11676
CAS No.: 1035154-49-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
