84852-53-9
Chemical Structure
Decabromodiphenyl ethane
Synonym(s): DBDPE; 1,2-Bis(perbromophenyl)ethane
- CAS No.: 84852-53-9
- Formula:C14H4Br10
- Molecular Weight:971.22
IUPAC Name: 1,2-bis(perbromophenyl)ethane
InChIKey: BZQKBFHEWDPQHD-UHFFFAOYSA-N
SMILES: BrC1=C(Br)C(Br)=C(CCC2=C(Br)C(Br)=C(Br)C(Br)=C2Br)C(Br)=C1Br
Biological Activity: Decabromodiphenyl ethane (DBDPE) is a brominated flame retardant. Decabromodiphenyl ethane induces ROS-related cytotoxicity and apoptosis in human hepatoma cells, causes hepatocyte damage through oxidative stress, endoplasmic reticulum stress and decreased CYP3A expression, and accumulates and undergoes biotransformation in animal tissues. Decabromodiphenyl ethane can be used to study the environmental toxicology and biological effects of brominated flame retardants[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Decabromodiphenyl ethane | 98.0% | Decabromodiphenyl ethane (DBDPE) is a brominated flame retardant. Decabromodiphenyl ethane induces ROS-related cytotoxicity and apoptosis in human hepatoma cells, causes hepatocyte damage through oxidative stress, endoplasmic reticulum stress and decreased CYP3A expression, and accumulates and undergoes biotransformation in animal tissues. Decabromodiphenyl ethane can be used to study the environmental toxicology and biological effects of brominated flame retardants. | ||||||||||||||||||||
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1,2-Bis(pentabromophenyl)ethane-13C14 | 1,2-Bis(pentabromophenyl)ethane-13C14 is 13C labeled 1,2-Bis(perbromophenyl)ethane. | |||||||||||||||||||||
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- [1]. Wang F, et al. Comparative Tissue Distribution, Biotransformation and Associated Biological Effects by Decabromodiphenyl Ethane and Decabrominated Diphenyl Ether in Male Rats after a 90-Day Oral Exposure Study. Environmental Science & Technology. 2010;44:5655-5660.
- [2]. Knudsen GA, et al. The biological fate of decabromodiphenyl ethane following oral, dermal or intravenous administration. Xenobiotica; the fate of foreign compounds in biological systems. 2017 Oct;47(10):894-902.
- [3]. Li J, Sun Y, et al. Oxidative stress and endoplasmic reticulum stress contributed to hepatotoxicity of decabromodiphenyl ethane (DBDPE) in L-02 cells. Chemosphere. 2022;286:131550.
- [4]. Sun RB, et al. Cytotoxicity and apoptosis induction in human HepG2 hepatoma cells by decabromodiphenyl ethane. Biomedical and environmental sciences : BES. 2012 Oct;25(5):495-501.
