614-75-5
614-75-5
Chemical Structure
2-Hydroxyphenylacetic acid
- CAS No.: 614-75-5
- Formula:C8H8O3
- Molecular Weight:152.15
IUPAC Name: 2-(2-hydroxyphenyl)acetic acid
InChIKey: CCVYRRGZDBSHFU-UHFFFAOYSA-N
SMILES: C1=CC=CC(=C1CC(O)=O)O
Biological Activity: 2-Hydroxyphenylacetic acid is a metabolite of Phenylalanine and Tyrosine, as well as a product of the biotransformation of Phenylacetonitrile by marine fungi. 2-Hydroxyphenylacetic acid acts as a potential biomarker for food. 2-Hydroxyphenylacetic acid slightly induces the expression of green fluorescent protein. 2-Hydroxyphenylacetic acid is used in the research of phenylketonuria and related hyperphenylalaninemia[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Hydroxyphenylacetic acid | 98.79% | 2-Hydroxyphenylacetic acid is a metabolite of Phenylalanine and Tyrosine, as well as a product of the biotransformation of Phenylacetonitrile by marine fungi. 2-Hydroxyphenylacetic acid acts as a potential biomarker for food. 2-Hydroxyphenylacetic acid slightly induces the expression of green fluorescent protein. 2-Hydroxyphenylacetic acid is used in the research of phenylketonuria and related hyperphenylalaninemia. | ||||||||||||||||||||
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2-Hydroxyphenylacetic acid (Standard) | ≥98% | 2-Hydroxyphenylacetic acid (Standard) is an analytical standard for 2-Hydroxyphenylacetic acid (HY-W015590). This product is intended for research and analytical applications. 2-Hydroxyphenylacetic acid is a metabolite of Phenylalanine and Tyrosine, and is also a product of the biotransformation of Phenylacetonitrile by marine fungi. 2-Hydroxyphenylacetic acid can be used as a potential biomarker for food. 2-Hydroxyphenylacetic acid can be used in the study of phenylketonuria and related hyperphenylalaninemias. | ||||||||||||||||||||
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DL-O-Tyrosine | 99.14% | DL-O-Tyrosine is a tyrosine derivative. | ||||||||||||||||||||
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Homogentisic acid (Standard) | 99.48% | Homogentisic acid (Standard) is the analytical standard of Homogentisic acid. This product is intended for research and analytical applications. Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid. | ||||||||||||||||||||
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Homogentisic acid-13C6 | 98.57% | Homogentisic acid-13C6 is the 13C-labeled Homogentisic acid (HY-113283). Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid. | ||||||||||||||||||||
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Salicylic acid (Standard) | 98.00% | Salicylic acid (Standard) is the analytical standard of Salicylic acid. This product is intended for research and analytical applications. Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. | ||||||||||||||||||||
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Salicylic acid-13C6 | 95.47% | Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity. | ||||||||||||||||||||
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2,4-Dihydroxyphenylacetic acid | 95.44% | 2,4-Dihydroxyphenylacetic acid (compound 3) is a natural product that can be obtained from Nigella damascene L. seeds. | ||||||||||||||||||||
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4-Hydroxyphenylacetic acid | 99.96% | 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2. | ||||||||||||||||||||
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3-Hydroxyphenylacetic acid | 99.03% | 3-Hydroxyphenylacetic acid is an orally active flavonoid metabolite produced by intestinal flora, with blood pressure-lowering activity. 3-Hydroxyphenylacetic acid can also inhibit ferroptosis by upregulating the expression of GPX4, thereby improving spermatogenic dysfunction in aged mice. In addition, abnormal levels of 3-Hydroxyphenylacetic acid are closely related to certain diseases, such as autism spectrum disorders. | ||||||||||||||||||||
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Melilotic acid (Standard) | 99.92% | Melilotic acid (Standard) is an analytical standard for Melilotic acid (HY-W017158). This product is intended for research and analytical applications. Melilotic acid (3-(2-hydroxyphenyl)-propanoic acid) is an orally active compound. Melilotic acid can be isolated from the bark of Chinese cinnamon. Melilotic acid has a significant inhibitory effect on gastric ulcers induced by serotonin (HY-B1473A), phenylbutazone (HY-B0230), ethanoyl, and water immersion stress. | ||||||||||||||||||||
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2-Fluorophenylacetic acid | 2-(2-Fluorophenyl)acetic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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References
- [1]. Mönch E, et al. Examination of urine metabolites in the newborn period and during protein loading tests at 6 months of age--Part 1. Eur J Pediatr. 1990;149 Suppl 1:S17-S24. [Content Brief]
- [2]. de Oliveira JR, et al. Biotransformation of phenylacetonitrile to 2-hydroxyphenylacetic acid by marine fungi. Mar Biotechnol (NY). 2013;15(1):97-103. [Content Brief]
- [3]. Guo KH, et al. Cell-Based Biosensor with Dual Signal Outputs for Simultaneous Quantification of Phenylacetic Acid and Phenylethylamine. ACS Synth Biol. 2018;7(12):2790-2795. [Content Brief]
