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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
Camptothecin analog
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "Camptothecin analog" in MCE Product Catalog:
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7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) .
Cat. No.: HY-164367
CAS No.: 2396667-62-0
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Mal-Bal-Ph(β-D-Glucose)-7-MAD-MDCPT (example 70) is an ADC drug-linker conjugate composed of the Camptothecin analog 7-MAD-MDCPT (HY-132162), and a Mal-Bal-Ph(β-D-Glucose) linker. DBCO-PEG2-C2-acid can be used to synthesize antibody-drug conjugates (ADCs) .
Cat. No.: HY-W021377
CAS No.: 182182-31-6
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Exatecan Intermediate 2 (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
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Deruxtecan analog 2 (example 9 P3) is a Deruxtecan (HY-13631E) analog. Deruxtecan analog 2 is a agent-linker conjugate composed of Camptothecin (HY-16560) and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC .
Cat. No.: HY-156756
CAS No.: 428816-69-7
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7-Hydroxymethyl-10,11-MDCPT is a hydrophilic camptothecin analog. 7-Hydroxymethyl-10,11-MDCPT is a payload that can be used for ADC synthesis .
Cat. No.: HY-132162A
CAS No.: 2740593-09-1
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7-MAD-MDCPT hydrochloride, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) .
Synonyms: GI147211; OSI-211
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Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects .
Cat. No.: HY-146269
CAS No.: 103816-16-6
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11-Desethyl Irinotecan is a camptothecin (CPT) analog and one of the metabolites of irinotecan. It is promising for cancer research .
Cat. No.: HY-W021377B
CAS No.: 2436720-50-0
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Exatecan Intermediate 4 (Compound 14f) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-156756S
Purity: 98.03%
Cat. No.: HY-W021377A
CAS No.: 2437603-23-9
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Exatecan Intermediate 2 hydrochloride (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-132162B
CAS No.: 2378428-15-8
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7-MAD-MDCPT TFA, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) .
Cat. No.: HY-156670
CAS No.: 2873460-51-4
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Camptothecin analog-1 (Comp 166) is a camptothecin analog .
Cat. No.: HY-178315
CAS No.: 2766214-00-8
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Exatecan analog 38 is a camptothecin derivative with potent topoisomerase I inhibitory activity. Exatecan analog 38 can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Exatecan analog 38 can be used for cancer research .
Cat. No.: HY-13670A
CAS No.: 155773-58-3
Synonyms: GI147211 dihydrochloride; OSI-211 dihydrochloride
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Lurtotecan dihydrochloride (GI147211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan dihydrochloride has anticancer effects .
Cat. No.: HY-164861
CAS No.: 3047369-35-4
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Camptothecin analog-2 (Compound 7b-2) is a camptothecin derivative. Camptothecin analog-2 can be used in the study of cancer .
Cat. No.: HY-19943
CAS No.: 1432468-79-5
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TLC388 is a novel camptothecin analog with limited antitumor activity in metastatic NEC .
Cat. No.: HY-14833
CAS No.: 867063-97-6
Synonyms: TP300
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Atiratecan (TP300) is a proagent of camptothecin analog CH0793076 (HY-107096). Atiratecan does not inhibit acetylcholinesterase (AChE) activities. Atiratecan shows antitumor activity against both breast cancer resistance protein (BCRP)-positive and -negative xenografts in mouse xenograft models .
Cat. No.: HY-162763
CAS No.: 794512-88-2
FLQY2 is a camptothecin analog that exhibits outstanding antitumor efficacy against various solid tumors. FLQY2 possesses both in vitro and in vivo anti-pancreatic cancer activity, inhibiting cell proliferation, colony formation, inducing apoptosis, and causing cell cycle arrest at nanomolar concentrations .
Cat. No.: HY-107096
CAS No.: 534605-78-2
Synonyms: TP3076
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CH-0793076 (TP3076), a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 inhibits DNA topoisomerase I with an IC50 of 2.3 μM. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
