2437603-23-9
Chemical Structure
Exatecan Intermediate 2 hydrochloride
- CAS No.: 2437603-23-9
- Formula:C13H16ClFN2O2
- Molecular Weight:286.73
IUPAC Name: N-(8-amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide hydrochloride
InChIKey: WELYDNOIIHGYEW-UHFFFAOYSA-N
SMILES: CC(NC(CCC1=C2C(N)=CC(F)=C1C)C2=O)=O.Cl
Biological Activity: Exatecan Intermediate 2 hydrochloride (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers[1].
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Exatecan Intermediate 2 hydrochloride | 99.94% | Exatecan Intermediate 2 hydrochloride (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers. | ||||||||||||||||||||
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Similarity Score 0.98
HY-W021377Exatecan Intermediate 2 -
Similarity Score 0.80
HY-43564Exatecan Intermediate 5 -
Similarity Score 0.78
HY-W021377BExatecan Intermediate 4 -
Similarity Score 0.67
HY-44369Exatecan Intermediate 6 -
Similarity Score 0.65
HY-45157Exatecan Intermediate 7 -
Similarity Score 0.55
HY-W999740CRBN ligand-227 -
Similarity Score 0.55
HY-W878657CRBN ligand-194 -
Similarity Score 0.53
HY-W898983CRBN ligand-181 -
Similarity Score 0.53
HY-46081Exatecan Intermediate 3 -
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