CRBN ligand-181
CRBN ligand-181 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 3036607-12-9
- Formula: C12H11BrFNO2
- Molecular Weight:300.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3036607-12-9
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Molecular Weight 300.12
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Formula C12H11BrFNO2
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SMILES
O=C(C(C1=C(C)C=C(Br)C=C1F)CC2)NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)