149882-10-0
149882-10-0
Chemical Structure
Lurtotecan
Synonym(s): GI147211; OSI-211
- CAS No.: 149882-10-0
- Formula:C28H30N4O6
- Molecular Weight:518.56
IUPAC Name: (S)-8-ethyl-8-hydroxy-15-((4-methylpiperazin-1-yl)methyl)-2,3,11,14-tetrahydro-12H-[1,4]dioxino[2,3-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-9,12(8H)-dione
InChIKey: RVFGKBWWUQOIOU-NDEPHWFRSA-N
SMILES: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CN5CCN(C)CC5)C6=CC(OCCO7)=C7C=C6N=C4C3=C2)=O
Biological Activity: Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects[1].
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Lurtotecan | Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects. | |||||||||||||||||||||
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References
Keywords
