1 Result for "

Cladophorol A

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Cladophorol A" in MCE Product Catalog:

Cat. No.: HY-N15159
CAS No.: 146776-30-9
Cladophorol A is a cyclic GMP-AMP synthase (cGAS) inhibitor. Cladophorol A binds to the conserved adenosine nucleobase binding site within the cGAS active site to inhibit its catalytic activity. Cladophorol A effectively inhibits the overactivation of the cGAS-STING pathway with an IC50 of 370 nM. Cladophorol A inhibits asexual blood-stage Plasmodium falciparum with an EC50 of 0.7 μg/mL. Cladophorol A can be used for the researches of inflammatory disease and malaria .
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