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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
Cu(I)
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "Cu(I)" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: Disodium bicinchoninate
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BCA is a chelating agent targeting Cu I. BCA forms a water-soluble complex with Cu I at a 2:1 stoichiometric ratio, which not only inhibits its oxidation and disproportionation reactions, but also mediates the Cu I-catalyzed azide-alkyne cycloaddition click chemistry reaction to achieve bioconjugation of fluorophores or biotin with functionalized proteins. BCA chelates Cu + from proteins that reduce Cu 2+, forming a purple compound detectable by colorimetry, and thus is used to determine the total protein concentration in solution. BCA is a potential small-molecule candidate for AHAS inhibitors .
8
8 Publications Verification
Cat. No.: HY-W004599
CAS No.: 1245-13-2
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Bicinchoninic acid is a chelating agent targeting Cu I. Bicinchoninic acid forms a water-soluble complex with Cu I at a 2:1 stoichiometric ratio, which not only inhibits its oxidation and disproportionation reactions, but also mediates the Cu I-catalyzed azide-alkyne cycloaddition click chemistry reaction to achieve bioconjugation of fluorophores or biotin with functionalized proteins. Bicinchoninic acid chelates Cu + from proteins that reduce Cu 2+, forming a purple compound detectable by colorimetry, and thus is used to determine the total protein concentration in solution. Bicinchoninic acid is a potential small-molecule candidate for AHAS inhibitors .
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8 Publications Verification
Cat. No.: HY-15908A
CAS No.: 63451-34-3
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Dipotassium [2,2'-biquinoline]-4,4'-dicarboxylate is a chelating agent targeting Cu I. Dipotassium [2,2'-biquinoline]-4,4'-dicarboxylate forms a water-soluble complex with Cu I at a 2:1 stoichiometric ratio, which not only inhibits its oxidation and disproportionation reactions, but also mediates the Cu I-catalyzed azide-alkyne cycloaddition click chemistry reaction to achieve bioconjugation of fluorophores or biotin with functionalized proteins. Dipotassium [2,2'-biquinoline]-4,4'-dicarboxylate chelates Cu + from proteins that reduce Cu 2+, forming a purple compound detectable by colorimetry, and thus is used to determine the total protein concentration in solution. Dipotassium [2,2'-biquinoline]-4,4'-dicarboxylate is a potential small-molecule candidate for AHAS inhibitors .
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2 Cited Publications
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BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF.
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Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals .
Cat. No.: HY-W800705
CAS No.: 1006592-61-5
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Tamra azide is an azide-terminated fluorescent dye and click reaction partner. Tamra azide undergoes Cu I-catalyzed cycloaddition click reaction with alkyne-functionalized nanodiamonds. After conjugation with nanodiamonds, Tamra azide serves as a fluorescent label that can be excited at a specific wavelength to exhibit characteristic luminescence (Ex/Em=555/580 nm) .
Cat. No.: HY-153419
CAS No.: 1334179-86-0
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BTTES is a tris(triazolylmethyl)amine-based ligand for Cu(I) without apparent toxicity. BTTES IMPROVES the cycloaddition reaction rapidly in living systems .
Cat. No.: HY-W753658
CAS No.: 1335151-56-8
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Coppersensor-3 (CS3) is a bright small-molecule fluorescent probe for selective Cu(I) detection. Coppersensor-3 is selective and sensitive enough to image labile copper pools in living cells at endogenous, basal levels. Coppersensor-3 can be used for the cell biology of copper research .
Cat. No.: HY-163200
CAS No.: 3034768-68-5
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Cu(I) chelator 1 (Compound LH2) is a chelator which targets the Cu(I) redox state. Cu(I) chelator 1 prevents ROS production .
Cat. No.: HY-W018008
CAS No.: 1271-47-2
Synonyms: Ferrocenylacetylene; Ferrocenylethyne
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Ethynylferrocene (Ferrocenylacetylene) is a click chemistry agent. Ethynylferrocene can be used for labeling of hairpin DNA probes to monitor the DNA hybridization via the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) .
Synonyms: 5-Azidovaleric acid
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5-Azidopentanoic acid (5-Azidovaleric acid) is a crosslinker/cyclization reagent as well as an azido-containing carboxylic acid. 5-Azidopentanoic acid participates in Cu I-catalyzed azide-alkyne cycloaddition reactions; when used to cap the N-terminus of resin-bound peptides containing propargylglycine residues, it enables head-to-tail cyclodimerization of peptides. 5-Azidopentanoic acid introduces azido functional groups into chitosan via amidation for strain-promoted azide-alkyne cycloaddition click reactions. 5-Azidopentanoic acid acts as an aliphatic bifunctional ligand and capping agent for CdSe tetrapods; its bromo group can be converted to an azido group, which then undergoes catalyst-free alkyne-azide cycloaddition click reactions with ethynyl-terminated poly (3-hexylthiophene) .
Cat. No.: HY-161181
CAS No.: 2223032-74-2
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BTTES-acid is an analog of BTTES. BTTES is a tris(triazolylmethyl)amine-based ligand for Cu(I) without apparent toxicity. BTTES improves the cycloaddition reaction rapidly in living systems .
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Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals .
Cat. No.: HY-151687
CAS No.: 1454816-10-4
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Fmoc-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Tyr(2-azidoethyl)-OH is unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. And azido-UAAs can be employed as IR reporters . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Cat. No.: HY-W1049767
CAS No.: 2088834-55-1
TIFSIX-2-Cu-i is a metal-organic framework (MOF).
Cat. No.: HY-W1049774
CAS No.: 2119615-01-7
SIFSIX-14-Cu-i is a metal-organic framework (MOF).
Cat. No.: HY-161436
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TPA-dT is a thymidine analog with a tris[(2-pyridyl)methyl]amine (TPA) group. TPA-dT can be used to modify siRNAs. The TPA-modified siRNAs remain functionally inactive and is incapable of silencing gene expression until the TPA moiety is removed upon exposure to Cu(I) .
Cat. No.: HY-W800697
CAS No.: 2644752-87-2
Cat. No.: HY-D3268
CAS No.: 1019329-49-7
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
