3 Results for "

D2R/β-arrestin-2 interactions

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "D2R/β-arrestin-2 interactions" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-111385
CAS No.: 2108826-33-9
Purity:  98.83%
UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride shows a binding affinity with a Ki of 79 nM for D2R. UNC9994 hydrochloride is also an antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride shows antipsychotic-like activity .
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Cat. No.: HY-116445
CAS No.: 1354030-19-5
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

UNC9975 is a D2R agonist that displays signaling bias via β-arrestin–ergic signaling and a simultaneously antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9975 can be utilized in antipsychotic research .
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Cat. No.: HY-111385R
CAS No.: 2108826-33-9
UNC9994 hydrochloride (Standard) is the analytical standard of UNC9994 (hydrochloride) (HY-111385). This product is intended for research and analytical applications. UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride shows a binding affinity with a Ki of 79 nM for D2R. UNC9994 hydrochloride is also an antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride shows antipsychotic-like activity .
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