2108826-33-9
Chemical Structure
UNC9994 hydrochloride
- CAS No.: 2108826-33-9
- Formula:C21H23Cl3N2OS
- Molecular Weight:457.84
IUPAC Name: 5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole hydrochloride
InChIKey: MTDQOQYYKZUEEK-UHFFFAOYSA-N
SMILES: ClC1=C(Cl)C(C2CCN(CCCOC3=CC=C(SC=N4)C4=C3)CC2)=CC=C1.Cl
Biological Activity: UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride shows a binding affinity with a Ki of 79 nM for D2R. UNC9994 hydrochloride is also an antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride shows antipsychotic-like activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
UNC9994 hydrochloride | 99.50% | UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride shows a binding affinity with a Ki of 79 nM for D2R. UNC9994 hydrochloride is also an antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride shows antipsychotic-like activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
UNC9994 hydrochloride (Standard) | ≥98% | UNC9994 hydrochloride (Standard) is the analytical standard of UNC9994 (hydrochloride) (HY-111385). This product is intended for research and analytical applications. UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride shows a binding affinity with a Ki of 79 nM for D2R. UNC9994 hydrochloride is also an antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride shows antipsychotic-like activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.98
HY-117829UNC9994 -
Similarity Score 0.73
HY-120920UNC9995 -
Similarity Score 0.54
HY-149335Sigma-1 receptor antagonist 5 -
Similarity Score 0.54
HY-155614KSK68 -
Similarity Score 0.53
HY-106831R 56865 -
Similarity Score 0.50
HY-101373Zolantidine -
Similarity Score 0.50
HY-18617rel-SB-612111 hydrochloride -
Similarity Score 0.50
HY-155615KSK67 -
Similarity Score 0.50
HY-105084Lubeluzole -
Explore the MedChemAI to find more analogs
