3 Results for "

EGFR-IN-138

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "EGFR-IN-138" in MCE Product Catalog:

EGFR-IN-138
EGFR-IN-138
0 Images
Cat. No.: HY-169428
Target:  

EGFR

Research Areas:  

Cancer

EGFR-IN-138 (compound 19) is a potent EGFR inhibitor，with IC50s of 37，2.6 and 1.9 nM for Wild-type，L858R and T790M EGFR，respectively .
loading...
    loading...
View All Sizes
5
PACAP (1-38), human, ovine, rat
PACAP (1-38), human, ovine, rat
0 Images
5 Cited Publications
Cat. No.: HY-P0221
CAS No.: 137061-48-4
Synonyms: Pituitary Adenylate Cyclase ActivatINg Polypeptide 38
Target:  

PACAP Receptor ERK EGFR Reactive Oxygen Species (ROS) Calcium Channel

Research Areas:  

Infection Neurological Disease

PACAP (1-38), human, ovine, rat is a PAC1 receptor agonist. PACAP (1-38), human, ovine, rat binds to PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 with IC50s of 4 nM, 2 nM, and 1 nM, respectively. PACAP (1-38), human, ovine, rat increases the α-secretase activity. PACAP (1-38), human, ovine, rat elevates cytosolic Ca 2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP (1-38), human, ovine, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP (1-38), human, ovine, rat can be used for neurotrophic and neuroprotective research .
loading...
    loading...
View All Sizes
PACAP (1-38), human, ovine, rat TFA
PACAP (1-38), human, ovine, rat TFA
0 Images
Cat. No.: HY-P0221A
Synonyms: Pituitary Adenylate Cyclase ActivatINg Polypeptide 38 TFA
Target:  

PACAP Receptor ERK EGFR Reactive Oxygen Species (ROS) Calcium Channel

Research Areas:  

Neurological Disease

PACAP (1-38), human, ovine, rat TFA is a PAC1 receptor agonist. PACAP (1-38), human, ovine, rat TFA binds to PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 with IC50s of 4 nM, 2 nM, and 1 nM, respectively. PACAP (1-38), human, ovine, rat TFA increases the α-secretase activity. PACAP (1-38), human, ovine, rat TFA elevates cytosolic Ca 2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP (1-38), human, ovine, rat TFA demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP (1-38), human, ovine, rat TFA can be used for neurotrophic and neuroprotective research .
loading...
    loading...
View All Sizes
Assay Types