Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
EI
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "EI" in MCE Product Catalog:
31
31 Publications Verification
Art. -Nr.: HY-17443
CAS. Nr.: 127373-66-4
Synonyms: EI546; LY544349; ONO5046
Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
31
31 Publications Verification
Art. -Nr.: HY-17443A
CAS. Nr.: 150374-95-1
Synonyms: ONO5046-Na; Sodium sivelestat; EI546 sodium; LY544349 sodium
Sivelestat (EI546) sodium is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
31
31 Publications Verification
Art. -Nr.: HY-17443B
CAS. Nr.: 201677-61-4
Synonyms: EI546 sodium tetrahydrate; LY544349 sodium tetrahydrate; ONO5046 sodium tetrahydrate
Sivelestat (EI546) sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
13
2
2 Cited Publications
Synonyms: KB-145943
Target:
Forschungsgebiete:
EI1 (KB-145943) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.
1
1 Cited Publications
Art. -Nr.: HY-P71303
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPINB1; Epididymis Secretory ProtEIn Li 27; Prev. ELANH2; Peptidase Inhibitor 2; MNEI; HEL-S-27; PI2; M/NEI; LEI; PI-2; EI; Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1, Isoform CRA_a; Leukocyte Elastase Inhibitor; Protease Inhibitor 2 (Ant
Species:
Human
Source:
HEK293
Art. -Nr.: HY-159838
CAS. Nr.: 2222689-47-4
Synonyms: EI‐1071
Forschungsgebiete:
Enrupatinib (EI‐1071) is a potent, orally active, CNS-penetrant and selective CSF1R inhibitor. Enrupatinib inhibits macrophage proliferation and osteoclast differentiation in vitro. Enrupatinib preserves microglia distal to Aβ plaques. Enrupatinib mitigates Alzheimer's disease (AD)-related pathologies by reducing neuroinflammation, preserving neuronal integrity, lowering disease-associated microglia gene expression, and enhancing cognitive function in 5xFAD and J20 mouse models. Enrupatinib reduces tumor-associated macrophage infiltration and enhances antitumor activity of anti-PD-1 antibody in murine colorectal cancer and breast cancer models. Enrupatinib can be used for the research of AD, colorectal cancer, and breast cancer .
Art. -Nr.: HY-B2049
CAS. Nr.: 64628-44-0
Target:
Forschungsgebiete:
Triflumuron is a potent chitin synthesis inhibitor. Triflumuron shows the efficacy in emergence inhibition (EI) against Culex quinquefasciatus and Aedes albopictus, with EI50 values of 5.28 and 1.59 μg/L, respectively. Triflumuron can be used as an insecticide. Triflumuron represents a potential tool for the control of disease vectors in public health .
Art. -Nr.: HY-17443R
CAS. Nr.: 127373-66-4
Synonyms: EI546 (Standard); LY544349 (Standard); ONO5046 (Standard)
Target:
Forschungsgebiete:
Sivelestat (Standard) is the analytical standard of Sivelestat. This product is intended for research and analytical applications. Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
Art. -Nr.: HY-P991002
CAS. Nr.: 2856372-57-9
Synonyms: EI-001
Target:
Forschungsgebiete:
Art. -Nr.: HY-D0921
CAS. Nr.: 162411-29-2
Synonyms: ADS 815EI
Art. -Nr.: HY-P1869
CAS. Nr.: 125934-45-4
Target:
Forschungsgebiete:
Art. -Nr.: HY-17443BR
CAS. Nr.: 201677-61-4
Synonyms: EI546 sodium tetrahydrate (Standard); LY544349 sodium tetrahydrate (Standard); ONO5046 sodium tetrahydrate (Standard)
Target:
Forschungsgebiete:
Sivelestat (sodium tetrahydrate) (Standard) is the analytical standard of Sivelestat (sodium tetrahydrate). This product is intended for research and analytical applications. Sivelestat (EI546) sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
Art. -Nr.: HY-RS04233
Target:
Forschungsgebiete:
EI24 Human Pre-designed siRNA Set A contains three designed siRNAs for EI24 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-138215
CAS. Nr.: 2414916-45-1
ADTL-EI1712 is a potent, orally active, and selective dual-target inhibitor of ERK1 and ERK5, inhibition rates of ERK1/5 at 1 μM are 93.54% and 89.35%, respectively. ADTL-EI1712 can induce regulated cell death, a form of cell death that relies on the activation of genetically encoded machinery, to overcome compensatory mechanism in specific cancer cells in vitro and in vivo .
Art. -Nr.: HY-116462
CAS. Nr.: 155023-59-9
Target:
Forschungsgebiete:
ONO-EI-601 is the major metabolite of human neutrophil elastase inhibitor ONO-5046. ONO-5046 has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
Art. -Nr.: HY-120410
CAS. Nr.: 1674389-55-9
Target:
Forschungsgebiete:
DL-4662 is a 3,4-dimethoxy derivative that can be identified using techniques such as, GC-EI-MS, LC-tandem mass spectrometry and NMR spectroscopy .
Art. -Nr.: HY-118932
CAS. Nr.: 301211-35-8
HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread .
Art. -Nr.: HY-161143
CAS. Nr.: 3029817-13-5
Forschungsgebiete:
Carbonic anhydrase/AChE-IN-2 (compound 19) is a selective acetylcholinesterase (AChE) and carbonic anhydrase (CA) inhibitor, with Ei of 5.07 nM, 24.42 nM and 19.95 nM for AChE, hCAI and hCAII, respectively .
Art. -Nr.: HY-RS12705
Target:
Forschungsgebiete:
SERPINB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SERPINB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
