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Results for "

EI

" in MedChemExpress (MCE) Product Catalog:

24

Inhibitors & Agonists

1

Fluorescent Dyes

1

Peptides

1

Inhibitory Antibodies

1

Natural
Products

1

Recombinant Proteins

6

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17443
    Sivelestat
    Maximum Cited Publications
    30 Publications Verification

    EI546; LY544349; ONO5046

    		 Elastase SARS-CoV Cancer
    Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
    Sivelestat
  • HY-17443A
    Sivelestat sodium
    Maximum Cited Publications
    30 Publications Verification

    ONO5046-Na; Sodium sivelestat; EI546 sodium; LY544349 sodium

    		 Elastase SARS-CoV Cancer
    Sivelestat (EI546) sodium is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
    Sivelestat sodium
  • HY-13804
    PP1
    10+ Cited Publications

    AGL 1872; EI 275

    		 Src Apoptosis Cancer
    PP1 is a potent, and Src family-selective tyrosine kinase inhibitor with IC50 of 5 and 6 nM for Lck and Fyn, respectively.
    PP1
  • HY-17443B
    Sivelestat sodium tetrahydrate
    Maximum Cited Publications
    30 Publications Verification

    EI546 sodium tetrahydrate; LY544349 sodium tetrahydrate; ONO5046 sodium tetrahydrate

    		 Elastase SARS-CoV Cancer
    Sivelestat (EI546) sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
    Sivelestat sodium tetrahydrate
  • HY-15573
    EI1
    2 Publications Verification

    KB-145943

    		 Histone Methyltransferase Apoptosis Cancer
    EI1 (KB-145943) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.
    EI1
  • HY-159838
    Enrupatinib

    EI‐1071

    		 c-Fms Amyloid-β Neurological Disease Cancer
    Enrupatinib (EI‐1071) is a potent, orally active, CNS-penetrant and selective CSF1R inhibitor. Enrupatinib inhibits macrophage proliferation and osteoclast differentiation in vitro. Enrupatinib preserves microglia distal to Aβ plaques. Enrupatinib mitigates Alzheimer's disease (AD)-related pathologies by reducing neuroinflammation, preserving neuronal integrity, lowering disease-associated microglia gene expression, and enhancing cognitive function in 5xFAD and J20 mouse models. Enrupatinib reduces tumor-associated macrophage infiltration and enhances antitumor activity of anti-PD-1 antibody in murine colorectal cancer and breast cancer models. Enrupatinib can be used for the research of AD, colorectal cancer, and breast cancer .
    Enrupatinib
  • HY-B2049
    Triflumuron

    		Environmental Pollutants Insecticide Infection
    Triflumuron is a potent chitin synthesis inhibitor. Triflumuron shows the efficacy in emergence inhibition (EI) against Culex quinquefasciatus and Aedes albopictus, with EI50 values of 5.28 and 1.59 μg/L, respectively. Triflumuron can be used as an insecticide. Triflumuron represents a potential tool for the control of disease vectors in public health .
    Triflumuron
  • HY-17443R
    Sivelestat (Standard)

    EI546 (Standard); LY544349 (Standard); ONO5046 (Standard)

    		 Elastase SARS-CoV Reference Standards Cancer
    Sivelestat (Standard) is the analytical standard of Sivelestat. This product is intended for research and analytical applications. Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
    Sivelestat (Standard)
  • HY-D0921
    Heptamethine cyanine dye-1

    ADS 815EI

    		 Fluorescent Dye Others
    Heptamethine cyanine dye-1 (Compound CyCl) is a cyanine dye (Fmax: 858 nm, in CH2Cl2). Heptamethine cyanine dye-1 can be used to synthesize pH near-infrared fluorescent probes .
    Heptamethine cyanine dye-1
  • HY-P1869
    Neuropeptide EI, rat

    		MCHR1 (GPR24) Melanocortin Receptor Neurological Disease Endocrinology
    Neuropeptide EI, rat displays functional melanin concentrating hormone (MCH)-antagonist and melanocyte-stimulating hormone (MSH) agonist activity in different behavioral paradigms .
    Neuropeptide EI, rat
  • HY-17443BR
    Sivelestat sodium tetrahydrate (Standard)

    EI546 sodium tetrahydrate (Standard); LY544349 sodium tetrahydrate (Standard); ONO5046 sodium tetrahydrate (Standard)

    		 Reference Standards Elastase SARS-CoV Cancer
    Sivelestat (sodium tetrahydrate) (Standard) is the analytical standard of Sivelestat (sodium tetrahydrate). This product is intended for research and analytical applications. Sivelestat (EI546) sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
    Sivelestat sodium tetrahydrate (Standard)
  • HY-RS04233
    EI24 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    EI24 Human Pre-designed siRNA Set A contains three designed siRNAs for EI24 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EI24 Human Pre-designed siRNA Set A
    EI24 Human Pre-designed siRNA Set A
  • HY-138215
    ADTL-EI1712

    		ERK Cancer
    ADTL-EI1712 is a potent, orally active, and selective dual-target inhibitor of ERK1 and ERK5, inhibition rates of ERK1/5 at 1 μM are 93.54% and 89.35%, respectively. ADTL-EI1712 can induce regulated cell death, a form of cell death that relies on the activation of genetically encoded machinery, to overcome compensatory mechanism in specific cancer cells in vitro and in vivo .
    ADTL-EI1712
  • HY-116462
    ONO-EI-601

    		Drug Metabolite Others
    ONO-EI-601 is the major metabolite of human neutrophil elastase inhibitor ONO-5046. ONO-5046 has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .
    ONO-EI-601
  • HY-120410
    DL-4662

    		Biochemical Assay Reagents Neurological Disease
    DL-4662 is a 3,4-dimethoxy derivative that can be identified using techniques such as, GC-EI-MS, LC-tandem mass spectrometry and NMR spectroscopy .
    DL-4662
  • HY-118932
    HCV-IN-45

    		HCV Infection
    HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread .
    HCV-IN-45
  • HY-161143
    Carbonic anhydrase/AChE-IN-2

    		Cholinesterase (ChE) Carbonic Anhydrase Neurological Disease
    Carbonic anhydrase/AChE-IN-2 (compound 19) is a selective acetylcholinesterase (AChE) and carbonic anhydrase (CA) inhibitor, with Ei of 5.07 nM, 24.42 nM and 19.95 nM for AChE, hCAI and hCAII, respectively .
    Carbonic anhydrase/AChE-IN-2
  • HY-RS12705
    SERPINB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SERPINB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SERPINB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SERPINB1 Human Pre-designed siRNA Set A
    SERPINB1 Human Pre-designed siRNA Set A
  • HY-RS22154
    Ei24 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ei24 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ei24 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ei24 Mouse Pre-designed siRNA Set A
    Ei24 Mouse Pre-designed siRNA Set A
  • HY-RS28676
    Ei24 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    Ei24 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ei24 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Ei24 Rat Pre-designed siRNA Set A
    Ei24 Rat Pre-designed siRNA Set A
  • HY-B2049R
    Triflumuron (Standard)

    		Insecticide Reference Standards Infection
    Triflumuron (Standard) is the analytical standard of Triflumuron. This product is intended for research and analytical applications. Triflumuron is a potent chitin synthesis inhibitor. Triflumuron shows the efficacy in emergence inhibition (EI) against Culex quinquefasciatus and Aedes albopictus, with EI50 values of 5.28 and 1.59 μg/L, respectively. Triflumuron can be used as an insecticide. Triflumuron represents a potential tool for the control of disease vectors in public health .
    Triflumuron (Standard)
  • HY-179654
    ST13

    		HDAC Apoptosis Cancer
    ST13, an ortho-hydroxyanilide, is a selective, slow- and tight-binding HDAC1 and HDAC2 inhibitor with IC50s of 23 nM and 49 nM, respectively. ST13 shows a weak inhibition of HDAC3 (IC50 = 4.30 μM) and HDAC6 (IC50 > 10 μM). The induced fit mechanism of ST13 proceeds through a two-step process: first, the enzyme and inhibitor rapidly form a collision complex (EI), which then slowly transforms into the stable complex E*I. ST13 induces apoptosis in cancer cells. ST13 can be used for the study of melanoma and triple-negative breast .
    ST13
  • HY-W667933
    S-Propyl-L-cysteine sulfoxide

    		Biochemical Assay Reagents Others
    S-Propyl-L-cysteine sulfoxide is an S-alkyl-L-cysteine sulfoxide and also a specific marker compound in Allium plants. S-Propyl-L-cysteine sulfoxide serves as a precursor of volatile alkyl disulfides, which produce the characteristic odor of Allium plants under the action of CS-lyase .
    S-Propyl-L-cysteine sulfoxide
  • HY-W741979A
    7,8-Dehydro pregnenolone

    		Drug Intermediate Others
    7,8-Dehydro pregnenolone is an endogenous 5,7-diene steroid present in fetal horse testes and ovaries. 7,8-Dehydro pregnenolone acts as an intermediate for biosynthesis of Dydrogesterone (HY-B0257A) .
    7,8-Dehydro pregnenolone

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