301211-35-8
301211-35-8
Chemical Structure
HCV-IN-45
- CAS. Nr.: 301211-35-8
- Formula:C16H19F3N6O3
- Molecular Weight:400.36
IUPAC Name: N2-(4-nitrophenyl)-N4-pentyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine
InChIKey: ZKEGXILVFBAJOX-UHFFFAOYSA-N
SMILES: FC(F)(COC1=NC(NC2=CC=C(C=C2)[N+]([O-])=O)=NC(NCCCCC)=N1)F
Biological Activity: HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread[1].
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HCV-IN-45 | HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread. | |||||||||||||||||||||
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