5 Results for "

Eg5 ATPase

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Eg5 ATPase" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-W011102
CAS No.: 2799-07-7
Synonyms: NSC 83265; S-Tritylcysteine; 3-Tritylthio-L-alanine
Target:  

Kinesin Apoptosis

Domaines de recherche:  

Cancer

S-Trityl-L-cysteine (NSC 83265) is a selective and allosteric kinesin Eg5 inhibitor with an IC50 of 1 μM for the inhibition of basal ATPase activity and 140 nM for the microtubule-activated ATPase activity. S-Trityl-L-cysteine has antitumor activities .
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Cat. No.: HY-16062
CAS No.: 1095253-39-6
Target:  

Kinesin

Domaines de recherche:  

Cancer

ARQ 621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division. Anti-tumor activity . ARQ 621 is a kinesin inhibitor . ARQ 621 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-119407
CAS No.: 167427-23-8
Target:  

Kinesin

Terpendole E is a mitotic kinesin Eg5 inhibitor. Terpendole E inhibits both motor and microtubule-stimulated ATPase activities of human Eg5. Terpendole E induces formation of a monoastral spindle in M phase .
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Cat. No.: HY-121816
CAS No.: 68705-66-8
Kolaflavanone is an biflavonoid allosteric inhibitor of Eg5. Kolaflavanone inhibits the ATPase and tyrosinase activities of Eg5 under both basal and microtubule-activated conditions, suppresses microtubule sliding activity, binds to the L5/α2/α3 allosteric pocket of Eg5, induces conformational changes of Eg5 and microtubule dissociation, interacts with aldehyde dehydrogenase, inhibits the ATPase activity of kinesin-1, and binds to HSA via pH-dependent forces. Kolaflavanone exhibits antihepatotoxic activity and can be used in studies related to Phalloidin (HY-P0028)-induced liver injury .
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Cat. No.: HY-W1143950
CAS No.: 25840-83-9
Target:  

Kinesin

Domaines de recherche:  

Cancer

O-Trityl-L-serine is an inhibitor of human mitotic kinesin Eg5, with a Ki app of 750 nM. O-Trityl-L-serine does not induce monopolar spindle formation or mitotic arrest in cancer cells. O-Trityl-L-serine can be used in cancer-related research .
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