O-Trityl-L-serine
O-Trityl-L-serine is an inhibitor of human mitotic kinesin Eg5, with a Kiapp of 750 nM. O-Trityl-L-serine does not induce monopolar spindle formation or mitotic arrest in cancer cells. O-Trityl-L-serine can be used in cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 25840-83-9
- Formula: C22H21NO3
- Molecular Weight:347.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Eg5 750 nM (Ki app) |
O-Trityl-L-serine (compound 34) inhibits the basal ATPase activity of human mitotic kinesin Eg5 in cell-free assays, with an apparent inhibition constant Kiapp of 750 nM[1].
O-Trityl-L-serine (5 μM; 8 h) does not induce mitotic arrest or monopolar spindle formation in HeLa cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 25840-83-9
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Molecular Weight 347.41
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Formula C22H21NO3
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SMILES
C(OC[C@@H](C(O)=O)N)(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
O-Trityl-L-serine Related Classifications
HY-W1143950 Related Classifications
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