167427-23-8
Chemical Structure
Terpendole E
- CAS No.: 167427-23-8
- Formula:C28H39NO3
- Molecular Weight:437.61
IUPAC Name: (2S,4R,4aR,4bR,6aS,12bS,12cS,14aS)-2-(2-hydroxypropan-2-yl)-4a,12b,12c-trimethyl-3,4,4a,4b,5,6,6a,7,12,12b,12c,13,14,14a-tetradecahydro-2H-chromeno[5',6':6,7]indeno[1,2-b]indol-4-ol
InChIKey: SVYIMXYKHRBHSG-KYYKPQATSA-N
SMILES: C[C@]12C3=C(C4=CC=CC=C4N3)C[C@]1([H])CC[C@]5([H])[C@@]2(CC[C@@]6([H])[C@]5([C@@H](C[C@H](O6)C(C)(O)C)O)C)C
Biological Activity: Terpendole E is a mitotic kinesin Eg5 inhibitor. Terpendole E inhibits both motor and microtubule-stimulated ATPase activities of human Eg5. Terpendole E induces formation of a monoastral spindle in M phase[1].
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Terpendole E | Terpendole E is a mitotic kinesin Eg5 inhibitor. Terpendole E inhibits both motor and microtubule-stimulated ATPase activities of human Eg5. Terpendole E induces formation of a monoastral spindle in M phase. | |||||||||||||||||||||
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Keywords
