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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Endonuclease IV
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Endonuclease IV" in MCE Product Catalog:
Cat. No.: HY-E70577
CAS No.: 63363-78-0
Target:
Research Areas:
DNA repair enzyme. Endonuclease IV has endonuclease activity at AP sites, 3' phosphodiesterase activity that can remove a variety of ligation-blocking lesions from the 3' end of DNA, endonuclease activity on oxidative DNA lesions, and 3' to 5' exonuclease activity .
APE1-IN-2 (compound AP1) is a Pt(IV) proagent, targeting a critical BER protein, apurinic/apyrimidinic endonuclease 1 (APE1). APE1-IN-2 shows anticancer activity. APE1-IN-2 induces intracellular accumulation of platinum and activates DNA damage response and apoptosis signals .
Cat. No.: HY-P700010
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FEN1; Flap Endonuclease 1; Prev. RAD2; Maturation Factor-1; FEN-1; Maturation Factor 1; MF1; HFEN-1; Flap Structure-Specific Endonuclease 1; DNase IV
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
