2923433-95-6
2923433-95-6
Chemical Structure
APE1-IN-2
- CAS No.: 2923433-95-6
- Formula:C9H12Cl2N4O5Pt
- Molecular Weight:522.21
IUPAC Name: 2-methyl-1-(3-methyl-4-(2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl)prop-2-en-1-one
InChIKey: OSYPHMCOKZJUOV-UHFFFAOYSA-J
SMILES: O[Pt](Cl)(Cl)(OC(C1=CC2=CC=CC([N+]([O-])=O)=C2N1)=O)([NH3])[NH3]
Biological Activity: APE1-IN-2 (compound AP1) is a Pt(IV) proagent, targeting a critical BER protein, apurinic/apyrimidinic endonuclease 1 (APE1). APE1-IN-2 shows anticancer activity. APE1-IN-2 induces intracellular accumulation of platinum and activates DNA damage response and apoptosis signals[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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APE1-IN-2 | 98.28% | APE1-IN-2 (compound AP1) is a Pt(IV) proagent, targeting a critical BER protein, apurinic/apyrimidinic endonuclease 1 (APE1). APE1-IN-2 shows anticancer activity. APE1-IN-2 induces intracellular accumulation of platinum and activates DNA damage response and apoptosis signals. | ||||||||||||||||||||
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