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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
F-actin cytoskeleton
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "F-actin cytoskeleton" in MCE Product Catalog:
25
25 Cited Publications
Cat. No.: HY-P0028
CAS No.: 17466-45-4
Target:
Research Areas:
Cat. No.: HY-P2031
CAS No.: 26645-35-2
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Cat. No.: HY-P10993
CAS No.: 1407967-57-0
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Research Areas:
Cat. No.: HY-12807A
CAS No.: 1781834-93-2
Synonyms: 5-Fluoro-2-indolyl deschlorohalopemide hydrochloride
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
FIPI hydrochloride is a phospholipase D (PLD) inhibitor with an IC50 for PLD1 and PLD2 of about 25 nM. FIPI hydrochloride regulates cytoskeletal recombination, cell diffusion and chemotaxis. FIPI hydrochloride can be used in cancer research. In addition, FIPI hydrochloride can enhance the secretion and aggregation of platelet dense particles, inhibit thrombosis, reduce ischemic stroke infarct volume and improve nerve function .
Cat. No.: HY-P75916
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LSP1; Pp52; Lymphocyte Specific Protein 1; F-actin Binding And cytoskeleton Associated Protein; WP34; Leufactin (Leukocyte F-actin Binding Protein); Lymphocyte-Specific Protein 1; 47 KDa actin Binding Protein; Lymphocyte-Specific Antigen WP34; Leukocyte-S
Species:
Human
Source:
HEK293
Cat. No.: HY-L060
2,299 compounds
The cytoskeleton is responsible for contraction, cell motility, movement of organelles and vesicles through the cytoplasm, cytokinesis, intracellular signal transduction, and many other functions that are essential for cellular homeostasis and survival. It accomplishes these tasks through three basic structures: F-actin, microtubules, and intermediate filaments (IFs). The cytoskeleton is a dynamic structure where the three major filaments and tubules are under the influence of proteins that regulate their length, state of polymerization, and level of cross-linking. Since cytoskeleton is involved in virtually all cellular processes, cytoskeletal protein aberrations are the underlying reason for many pathological phenotypes, including several cardiovascular disease syndromes, neurodegeneration, cancer, liver cirrhosis, pulmonary fibrosis, and blistering skin diseases.
MCE designs a unique collection of 2,299 cytoskeleton-related compounds mainly focusing on the key targets in the cytoskeleton signal pathway and can be used in the research of cytoskeleton signal pathway and related diseases.
Cat. No.: HY-117587
CAS No.: 1351592-10-3
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Research Areas:
EHT-6706 free base is a tubulin inhibitor with an IC50 value of 1 μM against porcine tubulin. EHT-6706 free base binds to the colchicine-binding site on tubulin to inhibit tubulin polymerization and disrupt the cellular microtubule network. EHT-6706 free base acts as an antiproliferative, vascular-disrupting, permeability-modulating, migration-inhibiting and antiangiogenic agent. EHT-6706 free base exhibits inhibitory activity against human tumor cells. EHT-6706 free base can be used in cancer and angiogenesis research .
Cat. No.: HY-184235
β-actin-IN-1 is a selective and covalent β-actin polymerization inhibitor. β-actin-IN-1 targets Cys272 of β-actin and shows selectivity over α-actin and γ-actin. β-actin-IN-1 inhibits β-actin polymerization and disrupts the actin cytoskeleton in cancer cells, leading to cell migration inhibition as well as cell death. β-actin-IN-1 can be used for the study of osteosarcoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
