1351592-10-3
Chemical Structure
EHT-6706 free base
- CAS No.: 1351592-10-3
- Formula:C21H24N2O4
- Molecular Weight:368.43
IUPAC Name: 7-ethoxy-4-(3,4,5-trimethoxybenzyl)isoquinolin-8-amine
InChIKey: INAKKEXXSTWCKJ-UHFFFAOYSA-N
SMILES: NC1=C(OCC)C=CC2=C1C=NC=C2CC3=CC(OC)=C(OC)C(OC)=C3
Biological Activity: EHT-6706 free base is a tubulin inhibitor with an IC50 value of 1 μM against porcine tubulin. EHT-6706 free base binds to the colchicine-binding site on tubulin to inhibit tubulin polymerization and disrupt the cellular microtubule network. EHT-6706 free base acts as an antiproliferative, vascular-disrupting, permeability-modulating, migration-inhibiting and antiangiogenic agent. EHT-6706 free base exhibits inhibitory activity against human tumor cells. EHT-6706 free base can be used in cancer and angiogenesis research[1].
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EHT-6706 free base | EHT-6706 free base is a tubulin inhibitor with an IC50 value of 1 μM against porcine tubulin. EHT-6706 free base binds to the colchicine-binding site on tubulin to inhibit tubulin polymerization and disrupt the cellular microtubule network. EHT-6706 free base acts as an antiproliferative, vascular-disrupting, permeability-modulating, migration-inhibiting and antiangiogenic agent. EHT-6706 free base exhibits inhibitory activity against human tumor cells. EHT-6706 free base can be used in cancer and angiogenesis research. | |||||||||||||||||||||
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