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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
55 Results for "
FCE 24304-d3
" in MedChemExpress (MCE) Product Catalog:
Products (55)
55 Results for "FCE 24304-d3" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: FCE-21336
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Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).
7
7 Cited Publications
Synonyms: FCE 24304; EXE
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Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .
2
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Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 μM) over MAO-A (IC50=580 μM) . Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8 μM) than at resting (IC50=262 μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al .
2
2 Cited Publications
Synonyms: FCE20124 mesylate; PNU155950E mesylate
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Reboxetine mesylate (FCE20124 mesylate) is a potent, selective, and specific noradrenaline reuptake inhibitor (NARI) for the research of depression. Reboxetine mesylate inhibits the uptake of norepinephrine, with a Ki of 8 nM .
2
2 Cited Publications
Cat. No.: HY-70057A
CAS No.: 202825-46-5
Synonyms: FCE 26743 mesylate; EMD 1195686 mesylate
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Safinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 μM) over MAO-A (IC50=580 nM) . Safinamide mesylate also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8 μM) than at resting (IC50=262 μM) potentials. Safinamide mesylate has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke et.al .
1
1 Cited Publications
Synonyms: Methoxymorpholinyl doxorubicin; FCE 23762; PNU 152243
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Nemorubicin (Methoxymorpholinyl doxorubicin) is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity .
1
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Ralfinamide (FCE-26742A) is an orally available Na + blocker derived from α-aminoamide, with function of suppressing pain .
1
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Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na + channel blocker derived from α-aminoamide, with function of suppressing pain .
Synonyms: FCE 28073; (R)-EMD 1195686
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(R)-Safinamide, the enantiomer of safinamide (HY-70057), can inhibit MAO-B with an IC50 value of 0.45 μM .
Synonyms: FCE 24517 hydrochloride
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Tallimustine hydrochloride, a distamycin-A derivative, is an anticancer agent .
Cat. No.: HY-15296R
CAS No.: 81409-90-7
Synonyms: FCE-21336 (Standard)
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Cabergoline (Standard) is the analytical standard of Cabergoline. This product is intended for research and analytical applications. Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).
Synonyms: FCE 24304(Standard); EXE (Standard)
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Exemestane (Standard) is the analytical standard of Exemestane. This product is intended for research and analytical applications. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .
Cat. No.: HY-165478
CAS No.: 155651-56-2
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FCE 28260 is an orally active 4-azacyclic 5α-reductase (5αR) inhibitor. FCE 28260 exhibits IC₅₀ values for human 5αR type 1 and 5αR type 2 of 36 and 3.3 nM, respectively, and for human and rat prostates with IC₅₀ values of 16 and 15 nM, respectively. FCE 28260 simultaneously blocks the production of dihydrotestosterone (DHT) in the prostate and peripheral tissues. FCE 28260 can significantly inhibit the induction of prostatic and seminal vesicle hyperplasia by testosterone (T) in rat models, without inhibiting the growth of the prostate in DHT implantation models. FCE 28260 can be used for the studies DHT-dependent diseases such as benign prostatic hyperplasia (BPH) .
Cat. No.: HY-70057S1
CAS No.: 2748522-33-8
Synonyms: FCE 26743-d4-1; EMD 1195686-d4-1
Cat. No.: HY-105217
CAS No.: 137099-09-3
Synonyms: FCE 26073
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Turosteride is a selective 5 alpha-reductase inhibitor, with IC50 values of 55 and 53 nM for human and rat prostatic 5 alpha-reductases, respectively. Turosteride can reduce the prostate and seminal vesicle weights .
Cat. No.: HY-70057R
CAS No.: 133865-89-1
Synonyms: FCE 26743 (Standard); EMD 1195686 (Standard)
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Safinamide (Standard) is the analytical standard of Safinamide. This product is intended for research and analytical applications. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 µM) . Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8 µM) than at resting (IC50=262 µM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al .
Cat. No.: HY-15296S1
CAS No.: 2738376-76-4
Synonyms: FCE-21336-d6
Cat. No.: HY-100158
CAS No.: 83359-86-8
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FCE-20696 hydrochloride is an orally active immunomodulator. FCE-20696 hydrochloride also shows anti-inflammation and anti-infection effects. FCE-20696 hydrochloride can be used for the researches of infection, inflammation and immunology, such as adjuvant arthritis .
Cat. No.: HY-108138
CAS No.: 120796-34-1
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FCE-25199 is an orally active penem antibiotic. FCE-25199 has antibacterial activity against various Gram positive and Gram negative bacteria. FCE-25199 is commonly used in the study of bacterial infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
