(R)-Safinamide
Based on 1 Customer Validation
(R)-Safinamide, the enantiomer of safinamide (HY-70057), can inhibit MAO-B with an IC50 value of 0.45 μM.
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 174756-44-6
- Formula: C17H19FN2O2
- Molecular Weight:302.34
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
IC50: 0.45 μM (MAO-B)[1].
Chemical Information
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CAS No. 174756-44-6
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Appearance Solid
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Molecular Weight 302.34
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Formula C17H19FN2O2
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Color White to off-white
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SMILES
FC1=CC=CC(COC2=CC=C(C=C2)CN[C@@H](C(N)=O)C)=C1
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Synonyms
FCE 28073; (R)-EMD 1195686
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 125 mg/mL (413.44 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3075 mL | 16.5377 mL | 33.0753 mL | 82.6884 mL |
| 5 mM | 0.6615 mL | 3.3075 mL | 6.6151 mL | 16.5377 mL | |
| 10 mM | 0.3308 mL | 1.6538 mL | 3.3075 mL | 8.2688 mL | |
| 15 mM | 0.2205 mL | 1.1025 mL | 2.2050 mL | 5.5126 mL | |
| 20 mM | 0.1654 mL | 0.8269 mL | 1.6538 mL | 4.1344 mL | |
| 25 mM | 0.1323 mL | 0.6615 mL | 1.3230 mL | 3.3075 mL | |
| 30 mM | 0.1103 mL | 0.5513 mL | 1.1025 mL | 2.7563 mL | |
| 40 mM | 0.0827 mL | 0.4134 mL | 0.8269 mL | 2.0672 mL | |
| 50 mM | 0.0662 mL | 0.3308 mL | 0.6615 mL | 1.6538 mL | |
| 60 mM | 0.0551 mL | 0.2756 mL | 0.5513 mL | 1.3781 mL | |
| 80 mM | 0.0413 mL | 0.2067 mL | 0.4134 mL | 1.0336 mL | |
| 100 mM | 0.0331 mL | 0.1654 mL | 0.3308 mL | 0.8269 mL |