1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. Ralfinamide mesylate

Ralfinamide mesylate  (Synonyms: FCE-26742A mesylate)

Cat. No.: HY-101437A
Handling Instructions

Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na+ channel blocker derived from α-aminoamide, with function of suppressing pain.

For research use only. We do not sell to patients.

Ralfinamide mesylate Chemical Structure

Ralfinamide mesylate Chemical Structure

CAS No. : 202825-45-4

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Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na+ channel blocker derived from α-aminoamide, with function of suppressing pain[1][2].

IC50 & Target


In Vivo

Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 81 adult male Sprague–Dawley male rats (260–460 g)[1]
Dosage: 80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)
Administration: Oral gavage; twice daily; until postoperative day 42
Result: Suppressed neuropathic pain.
Clinical Trial
Molecular Weight







Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

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Ralfinamide mesylate Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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