1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. Ralfinamide

Ralfinamide (Synonyms: FCE-26742A)

Cat. No.: HY-101437 Purity: 99.78%
Handling Instructions

Ralfinamide (FCE-26742A) is an orally available Na+ blocker derived from α-aminoamide, with function of suppressing pain.

For research use only. We do not sell to patients.

Ralfinamide Chemical Structure

Ralfinamide Chemical Structure

CAS No. : 133865-88-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 99 In-stock
Estimated Time of Arrival: December 31
10 mg USD 90 In-stock
Estimated Time of Arrival: December 31
50 mg USD 360 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Ralfinamide (FCE-26742A) is an orally available Na+ blocker derived from α-aminoamide, with function of suppressing pain[1][2].

IC50 & Target

Na+channel[1]

In Vivo

Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain[1].

Animal Model: 81 adult male Sprague–Dawley male rats (260–460 g)[1]
Dosage: 80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)
Administration: Oral gavage; twice daily; until postoperative day 42
Result: Suppressed neuropathic pain.
Clinical Trial
Molecular Weight

302.34

Formula

C₁₇H₁₉FN₂O₂

CAS No.

133865-88-0

SMILES

C[[email protected]](NCC1=CC=C(OCC2=CC=CC=C2F)C=C1)C(N)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (413.44 mM)

*"≥" means soluble, but saturation unknown.

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3075 mL 16.5377 mL 33.0753 mL
5 mM 0.6615 mL 3.3075 mL 6.6151 mL
10 mM 0.3308 mL 1.6538 mL 3.3075 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
Ralfinamide
Cat. No.:
HY-101437
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