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FRa

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By Targets:	ADC Antibody (2) Antibody-Drug Conjugates (ADCs) (1) Antifolate (1) Folate Receptor (FR) (1) Histamine Receptor (1) IFNAR (1) PARP (1) Small Interfering RNA (siRNA) (4) STAT (1) STING (1)
By Research Areas:	Cancer (4) Inflammation/Immunology (2)
Oligonucleotides:	Human Pre-designed siRNA Sets (4) siRNAs (4)

Inhibitors & Agonists

Inhibitory Antibodies

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99612

Farletuzumab ecteribulin MORAb-202	Antibody-Drug Conjugates (ADCs)	Cancer
Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity.

HY-17663

KMR-206	PARP STAT STING IFNAR	Cancer
KMR-206 is a PARP7 inhibitor with an IC₅₀ of 13.7 nM. KMR-206 relieves AHR-mediated transcriptional repression and enhances CYP1A1 expression in the presence of TCDD. KMR-206 induces the STING-dependent IFN-β signaling pathway and increases the levels of STAT1, pSTAT1 and nuclear PARP7 in cancer cells. KMR-206 reduces the viability of lung adenocarcinoma cells, enhances radiation-induced immunogenic signals, and induces the production of immunogenic signals in glioblastoma cancer stem cells. KMR-206 destabilizes *FRA1* to increase IRF1 levels and promotes the IRF3-CBP/p300 interaction. KMR-206 can be used in studies related to lung adenocarcinoma and glioblastoma .

HY-RS05034

FOSL1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FOSL1 Human Pre-designed siRNA Set A contains three designed siRNAs for FOSL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FOSL1 Human Pre-designed siRNA Set A FOSL1 Human Pre-designed siRNA Set A

HY-P990417

*Anti-FOLR1/FRA* Antibody**	Antifolate	Inflammation/Immunology
Anti-FOLR1/FRA Antibody is a humanized antibody expressed in CHO cells, targeting *FOLR1/FRA. The Anti-FOLR1/FRA* Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.46 kDa. The isotype control for the Anti-FOLR1/FRA Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-RS05088

FRA10AC1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FRA10AC1 Human Pre-designed siRNA Set A contains three designed siRNAs for FRA10AC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FRA10AC1 Human Pre-designed siRNA Set A FRA10AC1 Human Pre-designed siRNA Set A

HY-123728

FR-A-19	Histamine Receptor	Inflammation/Immunology
FR-A-19 is a potent histamine H2-agonist with IC₅₀ values of 0.02, 0.015, and 0.008 μM targets arpromidine, BUA-75, and FRA-19 respectively. FR-A-19 has potent anti-allergic properties .

HY-RS05089

FRAS1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FRAS1 Human Pre-designed siRNA Set A contains three designed siRNAs for FRAS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FRAS1 Human Pre-designed siRNA Set A FRAS1 Human Pre-designed siRNA Set A

HY-RS11583

RABEP2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RABEP2 Human Pre-designed siRNA Set A contains three designed siRNAs for RABEP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RABEP2 Human Pre-designed siRNA Set A RABEP2 Human Pre-designed siRNA Set A

HY-P992003

IKS012 Antibody IKS01 Antibody	ADC Antibody	Cancer
IKS012 (IKS01) Antibody is a monoclonal antibody inhibitor targeting folate receptor α (FRA). IKS012 Antibody can be used to synthesize the antibody-drug conjugate (ADC) IKS012. IKS012 Antibody can be used to research related to platinum-resistant ovarian cancer .

HY-P992515

ZW-191 Antibody	ADC Antibody Folate Receptor (FR)	Cancer
ZW-191 Antibody is a humanized IgG1 antibody targeting folate receptor α (FRα). ZW-191 Antibody is conjugated with MC-GGFG-AM-(10Me-11F-Camptothecin) (HY-153360) to generate the antibody-drug conjugate (ADC) ZW-191 (HY-185743). ZW-191 Antibody-based ADC exerts a potent bystander effect on both antigen-positive and antigen-negative cells. ZW-191 Antibody is applicable to research related to ovarian cancer, non-small cell lung cancer, endometrial cancer, and triple-negative breast cancer .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990417

*Anti-FOLR1/FRA* Antibody**	Antifolate	Inflammation/Immunology
Anti-FOLR1/FRA Antibody is a humanized antibody expressed in CHO cells, targeting *FOLR1/FRA. The Anti-FOLR1/FRA* Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.46 kDa. The isotype control for the Anti-FOLR1/FRA Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992003

IKS012 Antibody IKS01 Antibody	ADC Antibody	Cancer
IKS012 (IKS01) Antibody is a monoclonal antibody inhibitor targeting folate receptor α (FRA). IKS012 Antibody can be used to synthesize the antibody-drug conjugate (ADC) IKS012. IKS012 Antibody can be used to research related to platinum-resistant ovarian cancer .

HY-P992515

ZW-191 Antibody	ADC Antibody Folate Receptor (FR)	Cancer
ZW-191 Antibody is a humanized IgG1 antibody targeting folate receptor α (FRα). ZW-191 Antibody is conjugated with MC-GGFG-AM-(10Me-11F-Camptothecin) (HY-153360) to generate the antibody-drug conjugate (ADC) ZW-191 (HY-185743). ZW-191 Antibody-based ADC exerts a potent bystander effect on both antigen-positive and antigen-negative cells. ZW-191 Antibody is applicable to research related to ovarian cancer, non-small cell lung cancer, endometrial cancer, and triple-negative breast cancer .

Host:	Mouse (2) Rabbit (6)
Reactivity:	Human (8) Rat (3) Mouse (4)
Application:	IHC-P (5) ICC/IF (2) IP (3) WB (6) FC (5) ELISA (3)
Isotype:	IgG,Kappa (1) IgG (5) IgG1 (2)
Conjugation:	Non-conjugated (8)
Clonality:	Monoclonal (6) Recombinant (5)
Modification:	Unmodified (6)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84801

	RABEP2 Antibody (YA4498) FRa	IHC-P, FC, ELISA	Human
	RABEP2 Antibody (YA4498) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RABEP2.

HY-P84801A

	RABEP2 Antibody (YA4498)(PBS only) FRa	IHC-P, FC, ELISA	Human
	RABEP2 Antibody (YA4498) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RABEP2.

HY-P82282

	FRA1 Antibody (YA2027) FOSL1; FRa1; Fos-related antigen 1; FRa-1	WB, ICC/IF	Human
	FRA1 Antibody (YA2027) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FRA1.

HY-P82973

	FRA2 Antibody (YA2718) FOSL2; FRa2; Fos-related antigen 2; FRa-2	WB, IP, FC	Human, Mouse, Rat
	FRA2 Antibody (YA2718) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FRA2.

HY-P87902

	FRA1 Antibody (YA7587)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	FRA1 Antibody (YA7587) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to FRA1.

HY-P82932

	FHIT Antibody (YA2677) AP3A hydrolase; AP3Aase; Dinucleosidetriphosphatase; FRa3B	WB	Human, Rat
	FHIT Antibody (YA2677) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FHIT.

HY-P83570

	WWOX Antibody (YA3315) FOR; WOX1; EIEE28; FRa16D; SCAR12; HHCMA56; PRO0128; SDR41C1; D16S432E	WB, IHC-P, FC, IP	Human, Mouse
	WWOX Antibody (YA3315) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to WWOX.

HY-P83570A

	WWOX Antibody (YA3315)(PBS only) FOR; WOX1; EIEE28; FRa16D; SCAR12; HHCMA56; PRO0128; SDR41C1; D16S432E	WB, IHC-P, FC, IP	Human, Mouse
	WWOX Antibody (YA3315) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to WWOX.

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FOSL1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
FOSL1 Human Pre-designed siRNA Set A contains three designed siRNAs for FOSL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FRA10AC1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
FRA10AC1 Human Pre-designed siRNA Set A contains three designed siRNAs for FRA10AC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FRAS1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
FRAS1 Human Pre-designed siRNA Set A contains three designed siRNAs for FRAS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RABEP2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
RABEP2 Human Pre-designed siRNA Set A contains three designed siRNAs for RABEP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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