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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
99 Results for "
Factor X
" in MedChemExpress (MCE) Product Catalog:
Products (99)
99 Results for "Factor X" in MCE Product Catalog:
17
17 Publications Verification
Synonyms: Orin1001
MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29 μM in human vitro. MKC8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC50 of 0.52 μM and unstresses RPMI 8226 cells with an IC50 of 0.14 μM . MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibits prostate cancer (PCa) tumor growth .
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Peretinoin is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as retinoid X receptor (RXR) and retinoic acid receptor (RAR). Peretinoin reduces the mRNA level of sphingosine kinase 1 (SPHK1) in vitro by downregulating a transcription factor, Sp1 . Peretinoin prevents the progression of non-alcoholic steatohepatitis (NASH) and the development of hepatocellular carcinoma (HCC) through activating the autophagy pathway by increased Atg16L1 expression . Peretinoin inhibits HCV RNA amplification and virus release by altering lipid metabolism with a EC50 of 9 μM .
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5 Cited Publications
Mycro 3 is an orally active, potent and selective inhibitor of Myc-associated factor X (MAX) dimerization. Mycro 3 also inhibit DNA binding of c-Myc . Mycro 3 could be used for the research of pancreatic cancer .
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4 Cited Publications
Cat. No.: HY-N0712
CAS No.: 104472-68-6
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4
4 Cited Publications
Cat. No.: HY-P70569
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-8; IL-8; C-X-C Motif Chemokine 8; CXCL8; Emoctakin; Granulocyte Chemotactic Protein 1; GCP-1; Monocyte-Derived Neutrophil Chemotactic Factor; MDNCF; Monocyte-Derived Neutrophil-Activating Peptide; MONAP; Neutrophil-Activating Protein 1; NAP-1
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3 Cited Publications
Cat. No.: HY-P70469
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Stromal Cell-Derived Factor 1; SDF-1; hSDF-1; C-X-C Motif Chemokine 12; Intercrine Reduced in Hepatomas; IRH; hIRH; Pre-B Cell Growth-Stimulating Factor; PBSF; CXCL12; SDF1; SDF1A; SDF1B
2
1
1 Cited Publications
Cat. No.: HY-P1137
CAS No.: 955091-53-9
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Anisindione is an oral indandione anticoagulant. Anisindione inhibits the formation of active procoagulant factors II, VII, IX and X. Anisindione can be used in anticoagulation-related research .
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1
1 Cited Publications
Cat. No.: HY-P700219AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL12; Stromal cell-derived Factor 1; SDF-1; 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; TPAR1; C-X-C motif chemokine 12; Pre-B cell growth-stimulating Factor; PBSF; Thymic lymphoma cell-stimulating Factor; TLSF; Sdf1
1
1 Cited Publications
Cat. No.: HY-P702076
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1; HBV-associated Factor 4; Heme-oxidized IRP2 ubiquitin ligase 1; HOIL-1; Hepatitis B virus X-associated protein 4; RING finger protein 54; RING-type E3 ubiquitin transferase HOIL-1; Ubiquitin-conjugating enzyme 7-interacting protein 3
Cat. No.: HY-P9940
CAS No.: 1610943-06-0
Synonyms: ACE-910; RG6013
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Cat. No.: HY-E70544B
CAS No.: 9001-29-0
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Canine Factor X is prepared from freshly collected canine plasma and, after activation, can convert prothrombin to thrombin .
Cat. No.: HY-P990060
CAS No.: 2488745-86-2
Synonyms: Mim8
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Cat. No.: HY-N6987
CAS No.: 29913-71-1
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SPEN-IN-1 (compound X1) is an inhibitor of SPEN which is a protein factor with a Kd value of 47 nM. SPEN-IN-1 has high selectivity for RepA, a 431-nucleotide domain in Xist (a non-coding RNA prototype) that comprises 8.5 units of a GC-rich motif responsible for gene silencing .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
