3 Results for "

H2S prodrug

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "H2S prodrug" in MCE Product Catalog:

Cat. No.: HY-W014989
CAS No.: 20408-97-3
Thioglucose is a thiosugar with antioxidant properties. Thioglucose acts as an H2S/polysulfide donor to elevate intracellular sulfane sulfur levels and promote hydropersulfide formation. Thioglucose reduces the endocytosis of gold nanoparticles by phagocytes, enhances cytotoxicity and improves biocompatibility by increasing their adsorption on the surface of cancer cells. Thioglucose can be engineered into a stimulus-responsive prodrug or functional reagent for the development of targeted nanocarriers, and is used in studies related to human breast adenocarcinoma and cervical cancer .
loading...
    loading...
Cat. No.: HY-168639
Research Areas:  

Metabolic Disease

AP39 prodrug 1 (Compound M1) is a mitochondria-targeted H2S prodrug. AP39 prodrug 1 induces ROS-dependent mild mitochondrial uncoupling, activating mitochondria-associated AMPK to suppress Palmitic acid (PA) (HY-N0830)-induced lipid deposition in hepatocytes .
loading...
    loading...
Cat. No.: HY-186158
CAS No.: 1002722-97-5
Target:  

Drug Intermediate

Research Areas:  

Cancer

HOOC-OXA-COOH is an anionic prodrug of Oxaliplatin (HY-17371). HOOC-OXA-COOH can be loaded onto nanomotors via electrostatic interaction, and undergoes cascade activation by H2S and endogenous glutathione in the tumor microenvironment to release cytotoxic Pt 2+. HOOC-OXA-COOH can be used in the research of colon cancer .
loading...
    loading...