1002722-97-5
1002722-97-5
Chemical Structure
HOOC-OXA-COOH
- CAS. Nr.: 1002722-97-5
- Formula:C16H24N2O12Pt
- Molecular Weight:631.45
InChIKey: SSIYMPVUKUYYGS-NDSUJOINSA-H
SMILES: OC(CCC([O-][Pt+4]12([NH2][C@@]3([H])[C@](CCCC3)([H])[NH2]1)([O-]C(C([O-]2)=O)=O)[O-]C(CCC(O)=O)=O)=O)=O
Biological Activity: HOOC-OXA-COOH is an anionic prodrug of Oxaliplatin (HY-17371). HOOC-OXA-COOH can be loaded onto nanomotors via electrostatic interaction, and undergoes cascade activation by H2S and endogenous glutathione in the tumor microenvironment to release cytotoxic Pt2+. HOOC-OXA-COOH can be used in the research of colon cancer[1].
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HOOC-OXA-COOH | HOOC-OXA-COOH is an anionic prodrug of Oxaliplatin (HY-17371). HOOC-OXA-COOH can be loaded onto nanomotors via electrostatic interaction, and undergoes cascade activation by H2S and endogenous glutathione in the tumor microenvironment to release cytotoxic Pt2+. HOOC-OXA-COOH can be used in the research of colon cancer. | |||||||||||||||||||||
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References
Keywords
