7 Results for "

HER2-targeting peptide

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "HER2-targeting peptide" in MCE Product Catalog:

Cat. No.: HY-P10792
CAS No.: 1644155-35-0
Target:  

EGFR

Research Areas:  

Cancer

HER2-targeted peptide H6F is a HER2 targeting peptide that binds to HER2 to target breast cancer cells, with the amino acid sequence YLFFVFER. The HER2-targeted peptide H6F can be conjugated with the bifunctional chelating agent hydrazinonicotinamide (HYNIC) for radiolabeling with 99mTc. Single-photon emission computed tomography (SPECT) imaging shows that the labeled HER2-targeted peptide H6F specifically accumulates in HER2-positive MDA-MBA-453 tumor-bearing mice models. The HER2-targeted peptide H6F can be used for tumor molecular imaging studies .
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Cat. No.: HY-P10648
CAS No.: 3027722-28-4
Synonyms: HER2-targeting peptide
Target:  

EGFR

Research Areas:  

Cancer

Herceptide (HER2-targeting peptide) is a HER2-targeting peptide, and can be further conjugated to the near-infrared fluorescent dye indocyanine green (HY-D0711) (ICG) for developing theranostic agents .
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Cat. No.: HY-176976
CAS No.: 3076725-05-5
Research Areas:  

Cancer

Exatecan-mpGNNG (Compound 10a) is the linker-payload component of an antibody-drug conjugate (ADC). Exatecan-mpGNNG is composed of Exatecan (HY-13631), a potent topoisomerase I inhibitor, and the linker .
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Cat. No.: HY-P11760
CAS No.: 1802710-54-8
Target:  

EGFR

Research Areas:  

Cancer

HER2-targeted peptide H10 is a HER2-targeting peptide with a Kd value of 30.4 nM. HER2-targeted peptide H10 specifically accumulates in HER2-positive tumor tissues of xenograft mice, when conjugated with nanoparticles. HER2-targeted peptide H10 can be used for studies related to HER2-positive breast cancer .
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Cat. No.: HY-P11761
Target:  

EGFR

Research Areas:  

Cancer

HYNIC-H10F is a conjugate of HER2-targeting peptide H10F and bifunctional chelator HYNIC. HYNIC-H10F can be used in breast cancer-related research .
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Cat. No.: HY-P11613
Target:  

EGFR

Research Areas:  

Cancer

DOTA-WC8 is a HER2-targeting peptide probe with a KD of 61.20 nM. 68Ga-labeled DOTA-WC8 serves as a PET imaging agent for the specific identification of HER2-positive breast cancer. DOTA-WC8 is applicable to breast cancer-related research .
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Cat. No.: HY-P11590
Target:  

EGFR

Research Areas:  

Cancer

WGYRGFYC (WC8) is a selective HER2-targeting peptide that binds specifically to HER2 by mimicking the antigen-binding site of trastuzumab. The DOTA precursor of WGYRGFYC has a KD of 61.20 nM for HER2. WGYRGFYC enables specific and highly sensitive detection of HER2 expression in HER2-positive breast cancer cells and tumor tissues, and monitors the dynamic downregulation of HER2 expression. WGYRGFYC rapidly distributes to target tissues and is efficiently cleared from non-target tissues via the kidneys, generating an ideal tumor-to-background ratio in imaging; it is a component of the PET radiotracer Ga-DOTA-WC8. WGYRGFYC exhibits no significant cytotoxicity in breast cancer cells, and can be used for non-invasive imaging diagnosis and therapeutic efficacy evaluation of HER2-positive breast cancer .
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