23 Results for "

IL-12 receptor

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "IL-12 receptor" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W145667
CAS No.: 9036-88-8
Mannan is an orally active polysaccharide compound that binds to the mannose receptor (MR). Mannan promotes bacterial uptake and endosomal degradation by binding to MR, thereby enhancing the production of IL-12 in immune cells. Mannan enhances ROS production. Mannan modulates immunity, inhibits Aflatoxin B1 (HY-N6615)-induced toxicity, and reduces lipid .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P74834
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12RB2; IL-12R Subunit Beta-2; Interleukin 12 receptor Subunit Beta 2; Interleukin-12 receptor Beta-2 Chain; Interleukin-12 receptor Subunit Beta-2; IL-12R-Beta-2; Interleukin 12 receptor, Beta 2; IL-12RB2; IL-12 receptor Subunit Beta-2
Species:  
Mouse
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P99292
CAS No.: 326859-36-3
Synonyms: HuZAF; Anti-Human IFNG Recombinant Antibody

Target:  

IFNAR

Research Areas:  

Inflammation/Immunology

Fontolizumab (HuZAF) is a human monoclonal antibody targeting interferon γ (IFN-γ). Fontolizumab binds specifically and with high affinity to secreted IFN-γ, neutralizes its activity, blocks receptor binding, and inhibits downstream signal transduction and the expression of IFNγ-responsive genes. Fontolizumab reduces serum C-reactive protein levels, inhibits the expression of IL-1α, IL-1β and IL-12Rβ2, and decreases the number of IFNγ-producing T cells in activated peripheral blood mononuclear cells. Fontolizumab can be used in research related to Crohn's disease .
loading...
    loading...
Cat. No.: HY-176755
CAS No.: 943316-60-7
Research Areas:  

Inflammation/Immunology

CCL-34 is a Toll-like receptor 4 (TLR4) activator. CCL-34 significantly induced dendritic cell (DC) CD83 expression and IL-12p70 production in a dose-dependent manner, thereby inducing DC maturation. CCL-34 enhanced the allostimulatory activity of DC on naive CD4+CD45+RA+ T cell proliferation and IFN-γ secretion. CCL-34 further induced antigen presentation ability in mice inoculated with doxorubicin-treated colorectal cancer cells. CCL-34 can be used in studies of immune stimulation.
loading...
    loading...
Cat. No.: HY-P990224

Research Areas:  

Infection Cancer

Anti-Mouse IL-12 p75 Antibody (R2-9A5) is a rat-derived IgG2b κ type antibody inhibitor, targeting to mouse IL-12 p75. Anti-Mouse IL-12 p75 Antibody (R2-9A5) can neutralize IL-12. Anti-Mouse IL-12 p75 Antibody (R2-9A5) can be used for the researches of infection and cancer, such as E. coli infection and MCA205 sarcoma .
loading...
    loading...
Cat. No.: HY-174630
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL18R1 mRNA encodes the human interleukin 18 receptor 1 (IL18R1) protein, a cytokine receptor that belongs to the interleukin 1 receptor family. IL18R1 is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells.
loading...
    loading...
Cat. No.: HY-174616
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL23R mRNA encodes the human interleukin 23 receptor (IL23R) protein, a subunit of the receptor for IL23A/IL23. IL23R pairs with the receptor molecule IL12RB1/IL12R beta1, and both are required for IL23A signaling.
loading...
    loading...
Cat. No.: HY-174640
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL12RB1 mRNA encodes the human interleukin 12 receptor subunit beta 1 (IL12RB1) protein, a type I transmembrane protein that belongs to the hemopoietin receptor superfamily.
loading...
    loading...
Cat. No.: HY-162116
Research Areas:  

Inflammation/Immunology Cancer

TLR7 agonist 18 (Compound 21a) is a selective Toll-like receptor 7 (TLR7) agonist with an EC50 of 7.8 μM. TLR7 agonist 18 is not cytotoxic to hTLR7 cotransfected HEK293 cell lines and can induce the secretion of several cytokines, including IL-1β, IL-12p70, IL-8, and TNF-α. TLR7 agonist 18 can be used in vaccine, asthma, allergy and anti-cancer research .
loading...
    loading...
Cat. No.: HY-P811611
Synonyms: CD212, IL12R, IL12RB, IL12RB1, Interleukin-12 receptor subunit beta-1, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12RB1, IL-12 receptor beta component

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-168384
CAS No.: 875158-73-9
M04 is an agonist of STING. It induces the expression of the IFN reporter gene in HEK293T cells expressing wild-type human STING, but does not induce this expression in HEK293T cells expressing the R71H-G230A-R293Q (HAQ) STING variant or in mouse RAW 264.7 cells, indicating that its activity is dependent on allelic and species variations. M04 induces the production of TNF-α, IL-10, IL-1β, and IL-12p70 in human peripheral blood mononuclear cells (PBMCs). At a concentration of 50 µM, M04 stimulates dendritic cells isolated from PBMCs to express the MHC class II cell surface receptor HLA-DR and co-stimulatory molecules CD40, CD80, and CD86, and also enhances their ability to activate T cells in an ex vivo assay. M04 can be used in research on inflammatory immune diseases .
loading...
    loading...
Cat. No.: HY-P70647
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12RB1; Interleukin-12 receptor Beta-1 Chain; Prev. IL12RB; CD212 Antigen; CD212; IL-12R-Beta-1; Interleukin-12 receptor Subunit Beta-1; IL-12R-BETA1; Interleukin 12 receptor, Beta 1; IL-12RB1; IL-12 receptor Beta Component; IMD30; IL-12 receptor Subunit
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P704329
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL12RB1; Interleukin-12 receptor Beta-1 Chain; Prev. IL12RB; CD212 Antigen; CD212; IL-12R-Beta-1; Interleukin-12 receptor Subunit Beta-1; IL-12R-BETA1; Interleukin 12 receptor, Beta 1; IL-12RB1; IL-12 receptor Beta Component; IMD30; IL-12 receptor Subunit
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P78862
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12RB1; Interleukin-12 receptor Beta-1 Chain; Prev. IL12RB; CD212 Antigen; CD212; IL-12R-Beta-1; Interleukin-12 receptor Subunit Beta-1; IL-12R-BETA1; Interleukin 12 receptor, Beta 1; IL-12RB1; IL-12 receptor Beta Component; IMD30; IL-12 receptor Subunit
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P705155
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12RB1; Interleukin-12 receptor Beta-1 Chain; Prev. IL12RB; CD212 Antigen; CD212; IL-12R-Beta-1; Interleukin-12 receptor Subunit Beta-1; IL-12R-BETA1; Interleukin 12 receptor, Beta 1; IL-12RB1; IL-12 receptor Beta Component; IMD30; IL-12 receptor Subunit
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P705156
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12RB1; Interleukin-12 receptor Beta-1 Chain; Prev. IL12RB; CD212 Antigen; CD212; IL-12R-Beta-1; Interleukin-12 receptor Subunit Beta-1; IL-12R-BETA1; Interleukin 12 receptor, Beta 1; IL-12RB1; IL-12 receptor Beta Component; IMD30; IL-12 receptor Subunit
Species:  
Cynomolgus
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P72596
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12RB2; IL-12R Subunit Beta-2; Interleukin 12 receptor Subunit Beta 2; Interleukin-12 receptor Beta-2 Chain; Interleukin-12 receptor Subunit Beta-2; IL-12R-Beta-2; Interleukin 12 receptor, Beta 2; IL-12RB2; IL-12 receptor Subunit Beta-2
Species:  
Mouse
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P706120
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12RB2; IL-12R Subunit Beta-2; Interleukin 12 receptor Subunit Beta 2; Interleukin-12 receptor Beta-2 Chain; Interleukin-12 receptor Subunit Beta-2; IL-12R-Beta-2; Interleukin 12 receptor, Beta 2; IL-12RB2; IL-12 receptor Subunit Beta-2
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P705223
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL12RB2; IL-12R Subunit Beta-2; Interleukin 12 receptor Subunit Beta 2; Interleukin-12 receptor Beta-2 Chain; Interleukin-12 receptor Subunit Beta-2; IL-12R-Beta-2; Interleukin 12 receptor, Beta 2; IL-12RB2; IL-12 receptor Subunit Beta-2
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P992059

Target:  

CD1

Research Areas:  

Cancer

Anti-Mouse CD1d Antibody (1B1) is an antibody targeting mouse CD1d (Kd=12.5 nM). By inserting into the lipid-binding groove of CD1d, Anti-Mouse CD1d Antibody (1B1) overlaps with the binding sites of type I and type II NKT cell receptors (TCR), thereby effectively blocking TCR-mediated interactions. Anti-Mouse CD1d Antibody (1B1) activates antigen-presenting cells such as dendritic cells and macrophages, induces them to release IL-12p70, and increases the levels of key cytokines including IL-12, IFN-γ and IFN-α in mouse serum. Anti-Mouse CD1d Antibody (1B1) can be used in studies related to renal cancer, breast cancer and colon adenocarcinoma. When combined with anti-DR5 or anti-CD137 antibodies and chemotherapeutic drugs, Anti-Mouse CD1d Antibody (1B1) exhibits significant tumor inhibitory and even eradication effects in mice .
loading...
    loading...