Anti-Mouse IL-12 p75 Antibody (R2-9A5)
Anti-Mouse IL-12 p75 Antibody (R2-9A5) is a rat-derived IgG2b κ type antibody inhibitor, targeting to mouse IL-12 p75. Anti-Mouse IL-12 p75 Antibody (R2-9A5) can neutralize IL-12. Anti-Mouse IL-12 p75 Antibody (R2-9A5) can be used for the researches of infection and cancer, such as E. coli infection and MCA205 sarcoma.
For research use only. We do not sell to patients.
- Molecular Weight:150 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Isotype
Rat IgG2b kappa
Recommend Isotype Controls
Species Reactivity
Mouse
IC50 & Target
IL-12 p75
In Vitro
The antibody framework is stable, specific and adaptable, and has the ability to bind both antigens and endogenous immune receptors. Monoclonal antibodies have several derivatives, including bispecific antibodies, antibody-drug conjugates, and antibody fragments, and have significant effects in fields such as immunology and oncology. When designing inhibitory antibodies, considerations include identification of antigen-specific variable regions, choice of expression system, use of multispecific formats, and antibody derivatives based on fragmentation, oligomerization, or conjugation with other functional moieties[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Anti-Mouse IL-12 p75 Antibody (R2-9A5) (450 μg, i.p., 6 consecutive days starting the first day) inhibits the adjuvant properties of paired Toll-like receptor agonists in MCA205 sarcoma mice models[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Gene ID
Accession
P43431 & P43432
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Product Image
Application
in vivo IL-12p75 neutralization; ELISA
Chemical Information
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Molecular Weight 150 kDa
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SMILES
[Anti-Mouse IL-12 p75 Antibody (R2-9A5)]
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-Mouse IL-12 p75 Antibody (R2-9A5) Related Classifications
HY-P990224 Related Classifications
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