2. Gene
  3. Il12b - interleukin 12b Gene

Il12b - interleukin 12b Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p40; Il-12b; Il12p40; Il-12p40

Gene ID: 16160 | Gene type: protein coding

About Il12b

Chromosome 11: 44,290,890-44,304,860 forward strand.GRCm39:CM001004.3

This gene has 2 transcripts (splice variants), 268 orthologues and is associated with 19 phenotypes. Biased expression in thymus adult (RPKM 1.), spleen adult (RPKM .3) and 4 other tissues.

Summary

This gene encodes the beta subunit p40 of the Interleukin 12 (IL-12) family of cytokines. Members of the IL-12 family form heterodimers consisting of heavy and LIGHT subunits linked by disulfide bonds. The product of this gene, p40, is a subunit of interleukins IL-12 and IL-23. [provided by RefSeq, Dec 2014]

Il12b Products(1)

mRNA Protein Name
NM_001303244.1 NP_001290173.1 interleukin-12 subunit beta precursor

Il12b Protein Structure

Ig_3

Ig_3: pfam13927 (31 - 89)

Ig

Ig: cd00096 (45 - 49)

Ig

Ig: cd00096 (55 - 59)

Ig

Ig: cd00096 (72 - 76)

IL12p40_C

IL12p40_C: pfam10420 (122 - 213)

  • 0
  • 100
  • 200
  • 300
  • 335 a.a.
Protein Preferred Names Protein Names

interleukin-12 subunit beta

CLMF p40

IL-12 p40 subunit

IL-12 subunit p40

IL-23 subunit p40

cytotoxic lymphocyte maturation factor 40 kDa subunit

interleukin-12 p40 subunit

Recombinant Il12b Proteins

Cat. No. Product Name Accession Purity
HY-P7208 IL-12 Protein, Mouse (CHO) P43431 (R23-A215) & P43432 (M23-S335) ≥95%
HY-P70421 IL-23 alpha (175a.a) & IL-12 beta (313a.a) Heterodimer Protein, Mouse (Sf9) Q9EQ14 (V22-A196)&P43432 (M23-S335 ) ≥95%
HY-P70604 IL-23 alpha (175a.a) & IL-12 beta (313a.a) Heterodimer Protein, Mouse (HEK293, C-His) Q9EQ14 (V22-A196)&P43432 (M23-S335) ≥95%
HY-P70666 IL-12 Protein, Mouse (HEK293) P43431 (R23-A215) & P43432 (M23-S335) ≥95%
HY-P70709 IL-23 alpha (175a.a) & IL-12 beta (313a.a) Heterodimer Protein, Mouse (HEK293) Q9EQ14 (V22-A196)&P43432 (M23-S335) ≥95%
HY-P72771 Human IL-23A & Mouse IL-12B Heterodimer Protein (HEK293, His) Q9NPF7 (R20-P189)&P43432 (M23-S335) ≥95%
HY-P72597 IL-12 beta Protein, Mouse (HEK293, His) P43432 (M23-S335) ≥95%
HY-P73157 IL-12 Protein, Mouse (HEK293, Fc) P43431 (R23-A215) & P43432 (M23-S335) ≥95%
HY-P73158 IL-12 Protein, Mouse (HEK293, His-Fc) P43431 (R23-A215) & P43432 (M23-S335) ≥95%
HY-P73159 IL-12 Protein, Mouse (HEK293, His) P43431 (R23-A215) & P43432 (M23-S335) ≥95%
HY-P73161 IL-12 beta Protein, Mouse (HEK293) P43432 (M23-S335) ≥95%
HY-P73162 IL-12 beta Protein, Mouse (HEK293, Fc) P43432 (M23-S335) ≥95%
HY-P73163 IL-12 beta Protein, Mouse (335a.a, HEK293, His) P43432 (M1-S335) ≥95%
HY-P74874 Human IL-23 alpha & Mouse IL-12 beta Heterodimer Protein (HEK293, His) Q9NPF7 (R20-P189)&P43432 (M23-S335) ≥95%
HY-P77703 Cynomolgus IL-23 alpha & Mouse IL-12 beta Heterodimer Protein (HEK293, His) A0A2K5TLV4 (V22-P189)&P43432 (M23-S335) ≥95%
HY-P77705 IL-23 alpha (175a.a) & IL-12 beta (313a.a) Heterodimer Protein, Mouse (HEK293, N-His) Q9EQ14 (V22-A196)&P43432 (M23-S335) ≥95%
HY-P77712 Human IL-23 alpha & Mouse IL-12 beta Heterodimer Protein (HEK293, His-Avi) Q9NPF7 (I20-P189)&P43432 (M23-S335) ≥95%
HY-P78152 IL-23 alpha Protein, Mouse (Biotinylated, HEK293, His-Avi) Q9EQ14 (V22-A196) ≥95%
HY-P78861 IL-12 beta Protein, Mouse (Biotinylated, HEK293, His-Avi) P43432 (M23-S335) ≥95%
HY-P74814 IL-23 alpha (175a.a) & IL-12 beta (313a.a) Heterodimer Protein, Mouse (HEK293, His) Q9EQ14 (V22-A196)&P43432 (M23-S335) ≥95%
HY-P700191AF Animal-Free IL-12 beta Protein, Mouse (His) P43432 (M23-S335) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06680 IL12B Human Pre-designed siRNA Set A / Unkown
HY-RS06681 Il12b Mouse Pre-designed siRNA Set A / Unkown
HY-RS06682 Il12b Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il12b NCBI NCBI:3593
Rattus norvegicus Il12b NCBI NCBI:64546