10 Results for "

IL-21 Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "IL-21 Antibody" in MCE Product Catalog:

Cat. No.: HY-P991272
Synonyms: PF-05230900

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

ATR-107 (PF-05230900) is a humanized monoclonal antibody inhibitor that targets the interleukin-21 receptor (IL-21R). The Ka value of ATR-107 is 2-4 nM in cynomolgus monkeys, 16 nM in mice, and 71 nM in rats. ATR-107 can be used in research related to systemic lupus erythematosus and air pouch inflammation .
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Cat. No.: HY-P991271
Synonyms: NNC-114-0005; NN9828; NNC01140006
NN-8828 (NNC-114-0005; NN9828; NNC01140006) is a human IgG1 monoclonal antibody inhibitor targeting IL-21 that binds and neutralizes soluble IL-21 with a Kd of 0.19 pM. NN-8828 restores the balance between effector T cells and regulatory T cells, inhibits pathological antibody production, and alleviates IL-21-mediated inflammatory responses without inducing antibody-dependent cellular cytotoxicity. NN-8828 exhibits favorable biosafety. NN-8828 can be used in research related to rheumatoid arthritis, type 1 diabetes, and systemic lupus erythematosus .
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Cat. No.: HY-P99687
CAS No.: 2552814-07-8
Synonyms: AMG 256

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Latikafusp (AMG 256) is a bifunctional fusion protein comprising a PD-1-targeting antibody and IL-21 mutein designed to deliver IL-21 pathway stimulation to PD-1+ cells. Latikafusp is designed to prime and extend the activity of cytotoxic and memory T cells and induce anti-tumor immunity. Latikafusp has the potential for solid tumors research .Latikafusp may lead to the development of immunogenicity-mediated responses .
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Cat. No.: HY-P990218
Anti-Mouse IL-21R Antibody (4A9) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-21R. Anti-Mouse IL-21R Antibody (4A9) blocks IL-21 signaling. Anti-Mouse IL-21R Antibody (4A9) can be used for the researches of cancer, infection immunology and inflammation, such as psoriasis, hepatocellular carcinoma and C. rodentium infection .
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Cat. No.: HY-P990449

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-IL-21 Antibody is a humanized antibody expressed in CHO cells that targets IL-21. The Anti-IL-21 Antibody contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.32 kDa. The isotype control for Anti-IL-21 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P992241

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-IL-21R Antibody is a monoclonal antibody targeting IL-21R. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-IL-21R Antibody, please refer to Human IgG1 (L234A/L235A) kappa, Isotype Control (HY-P991207).
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Cat. No.: HY-P84784
Synonyms: TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23

Host:  

Mouse

Application:  

IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84784A
Synonyms: TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23

Host:  

Mouse

Application:  

IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84805
Synonyms: IL21R; NILR; IMD56

Host:  

Mouse

Application:  

ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84805A
Synonyms: IL21R; NILR; IMD56

Host:  

Mouse

Application:  

ICC/IF, FC, ELISA

Reactivity:  

Human

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